LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PF477736 | 10 | uM | LJP5 | 72 | hr | 1209 | 1268 | 4203 | 0.3019 | 0.0262 |
| MCF7 | LDN-193189 | 0.04 | uM | LJP5 | 72 | hr | 1209 | 4394 | 4203 | 1.0467 | 1.0523 |
| MCF7 | LDN-193189 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 4506 | 4203 | 1.0727 | 1.0803 |
| MCF7 | LDN-193189 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 4049 | 4203 | 0.9659 | 0.9629 |
| MCF7 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3535 | 4203 | 0.8416 | 0.8169 |
| MCF7 | LDN-193189 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 967 | 4203 | 0.2296 | -0.1197 |
| MCF7 | LDN-193189 | 10 | uM | LJP5 | 72 | hr | 1209 | 502 | 4203 | 0.1197 | -0.3886 |
| MCF7 | PF431396 | 0.04 | uM | LJP5 | 72 | hr | 1209 | 3174 | 4203 | 0.7570 | 0.7129 |
| MCF7 | PF431396 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 2380 | 4203 | 0.5676 | 0.4586 |
| MCF7 | PF431396 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 1470 | 4203 | 0.3509 | 0.1156 |
| MCF7 | PF431396 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1289 | 4203 | 0.3075 | 0.0365 |
| MCF7 | PF431396 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 1069 | 4203 | 0.2555 | -0.0661 |
| MCF7 | PF431396 | 10 | uM | LJP5 | 72 | hr | 1209 | 642 | 4203 | 0.1532 | -0.2974 |
| MCF7 | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 1209 | 4182 | 4012 | 1.0446 | 1.0523 |
| MCF7 | Celastrol | 0.12 | uM | LJP6 | 72 | hr | 1209 | 3933 | 4012 | 0.9828 | 0.9811 |
| MCF7 | Celastrol | 0.37 | uM | LJP6 | 72 | hr | 1209 | 2695 | 4012 | 0.6726 | 0.5903 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1395 | 4012 | 0.3481 | 0.0860 |
| MCF7 | Celastrol | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1009 | 4012 | 0.2526 | -0.0995 |
| MCF7 | Celastrol | 10 | uM | LJP6 | 72 | hr | 1209 | 525 | 4012 | 0.1312 | -0.3830 |
| MCF7 | SU11274 | 0.04 | uM | LJP5 | 72 | hr | 1209 | 4485 | 4203 | 1.0671 | 1.0727 |
| MCF7 | SU11274 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 4202 | 4203 | 0.9978 | 0.9950 |
| MCF7 | SU11274 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 3974 | 4203 | 0.9467 | 0.9404 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3609 | 4203 | 0.8600 | 0.8394 |
| MCF7 | SU11274 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 3108 | 4203 | 0.7394 | 0.6899 |
| MCF7 | SU11274 | 10 | uM | LJP5 | 72 | hr | 1209 | 1328 | 4203 | 0.3168 | 0.0538 |