LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 CHIR-99021
0.37
uM
LJP6
 72
hr
 1311 4269 4935 0.8651 0.8537
MDA-MB-231 CHIR-99021
1.11
uM
LJP6
 72
hr
 1311 4451 4935 0.9019 0.8949
MDA-MB-231 CHIR-99021
3.33
uM
LJP6
 72
hr
 1311 4289 4935 0.8695 0.8587
MDA-MB-231 CHIR-99021
10
uM
LJP6
 72
hr
 1311 3723 4935 0.7546 0.7258
MDA-MB-231 Linifanib
0.04
uM
LJP6
 72
hr
 1311 5333 4935 1.0806 1.0826
MDA-MB-231 Linifanib
0.12
uM
LJP6
 72
hr
 1311 5238 4935 1.0611 1.0623
MDA-MB-231 Linifanib
0.37
uM
LJP6
 72
hr
 1311 5129 4935 1.0392 1.0406
MDA-MB-231 Linifanib
1.11
uM
LJP6
 72
hr
 1311 5005 4935 1.0143 1.0146
MDA-MB-231 Linifanib
3.33
uM
LJP6
 72
hr
 1311 4959 4935 1.0050 1.0049
MDA-MB-231 Linifanib
10
uM
LJP6
 72
hr
 1311 2666 4935 0.5404 0.4493
MDA-MB-231 PIK-93
0.04
uM
LJP5
 72
hr
 1311 5214 5079 1.0265 1.0269
MDA-MB-231 PIK-93
0.12
uM
LJP5
 72
hr
 1311 5226 5079 1.0295 1.0296
MDA-MB-231 PIK-93
0.37
uM
LJP5
 72
hr
 1311 5165 5079 1.0171 1.0173
MDA-MB-231 PIK-93
1.11
uM
LJP5
 72
hr
 1311 4779 5079 0.9415 0.9387
MDA-MB-231 PIK-93
3.33
uM
LJP5
 72
hr
 1311 4073 5079 0.8023 0.7865
MDA-MB-231 PIK-93
10
uM
LJP5
 72
hr
 1311 2075 5079 0.4088 0.2647
MDA-MB-231 Dactolisib
0.04
uM
LJP5
 72
hr
 1311 2836 5079 0.5586 0.4839
MDA-MB-231 Dactolisib
0.12
uM
LJP5
 72
hr
 1311 2402 5079 0.4729 0.3630
MDA-MB-231 Dactolisib
0.37
uM
LJP5
 72
hr
 1311 2036 5079 0.4010 0.2522
MDA-MB-231 Dactolisib
1.11
uM
LJP5
 72
hr
 1311 2084 5079 0.4104 0.2670
MDA-MB-231 Dactolisib
3.33
uM
LJP5
 72
hr
 1311 2071 5079 0.4077 0.2632
MDA-MB-231 Dactolisib
10
uM
LJP5
 72
hr
 1311 2172 5079 0.4278 0.2945
MDA-MB-231 Alpelisib
0.04
uM
LJP5
 72
hr
 1311 5183 5079 1.0207 1.0211
MDA-MB-231 Alpelisib
0.12
uM
LJP5
 72
hr
 1311 5184 5079 1.0208 1.0208
MDA-MB-231 Alpelisib
0.37
uM
LJP5
 72
hr
 1311 4992 5079 0.9829 0.9816