LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Linifanib
0.12
uM
LJP6
 72
hr
 1694 11792 11217 1.0512 1.0369
MCF 10A Linifanib
0.37
uM
LJP6
 72
hr
 1694 11418 11217 1.0180 1.0131
MCF 10A Linifanib
1.11
uM
LJP6
 72
hr
 1694 11428 11217 1.0188 1.0136
MCF 10A Linifanib
3.33
uM
LJP6
 72
hr
 1694 11019 11217 0.9823 0.9869
MCF 10A Linifanib
10
uM
LJP6
 72
hr
 1694 9388 11217 0.8369 0.8734
MCF 10A PIK-93
0.04
uM
LJP5
 72
hr
 1694 11144 11103 1.0036 1.0027
MCF 10A PIK-93
0.12
uM
LJP5
 72
hr
 1694 11269 11103 1.0149 1.0109
MCF 10A PIK-93
0.37
uM
LJP5
 72
hr
 1694 11351 11103 1.0223 1.0163
MCF 10A PIK-93
1.11
uM
LJP5
 72
hr
 1694 10884 11103 0.9803 0.9854
MCF 10A PIK-93
3.33
uM
LJP5
 72
hr
 1694 9476 11103 0.8534 0.8864
MCF 10A PIK-93
10
uM
LJP5
 72
hr
 1694 5474 11103 0.4930 0.5407
MCF 10A Dactolisib
0.04
uM
LJP5
 72
hr
 1694 6617 11103 0.5959 0.6522
MCF 10A Dactolisib
0.12
uM
LJP5
 72
hr
 1694 4098 11103 0.3691 0.3846
MCF 10A Dactolisib
0.37
uM
LJP5
 72
hr
 1694 2879 11103 0.2593 0.2149
MCF 10A Dactolisib
1.11
uM
LJP5
 72
hr
 1694 2858 11103 0.2574 0.2119
MCF 10A Dactolisib
3.33
uM
LJP5
 72
hr
 1694 2934 11103 0.2643 0.2241
MCF 10A Dactolisib
10
uM
LJP5
 72
hr
 1694 2976 11103 0.2681 0.2299
MCF 10A Alpelisib
0.04
uM
LJP5
 72
hr
 1694 10662 11103 0.9603 0.9703
MCF 10A Alpelisib
0.12
uM
LJP5
 72
hr
 1694 9995 11103 0.9001 0.9238
MCF 10A Alpelisib
0.37
uM
LJP5
 72
hr
 1694 9524 11103 0.8578 0.8900
MCF 10A Alpelisib
1.11
uM
LJP5
 72
hr
 1694 9390 11103 0.8458 0.8799
MCF 10A Alpelisib
3.33
uM
LJP5
 72
hr
 1694 8246 11103 0.7427 0.7923
MCF 10A Alpelisib
10
uM
LJP5
 72
hr
 1694 4789 11103 0.4313 0.4665
MCF 10A GDC-0980
0.04
uM
LJP5
 72
hr
 1694 10202 11103 0.9188 0.9384
MCF 10A GDC-0980
0.12
uM
LJP5
 72
hr
 1694 7230 11103 0.6512 0.7074