LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | GDC-0980 | 0.37 | uM | LJP5 | 72 | hr | 1694 | 4209 | 11103 | 0.3792 | 0.3986 |
MCF 10A | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2526 | 11103 | 0.2276 | 0.1579 |
MCF 10A | GDC-0980 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 2387 | 11103 | 0.2151 | 0.1338 |
MCF 10A | GDC-0980 | 10 | uM | LJP5 | 72 | hr | 1694 | 2118 | 11103 | 0.1908 | 0.0853 |
MCF 10A | Mitoxantrone | 0.04 | uM | LJP5 | 72 | hr | 1694 | 3239 | 11103 | 0.2917 | 0.2696 |
MCF 10A | Mitoxantrone | 0.04 | uM | LJP6 | 72 | hr | 1694 | 3196 | 11217 | 0.2850 | 0.2620 |
MCF 10A | Mitoxantrone | 0.12 | uM | LJP5 | 72 | hr | 1694 | 1687 | 11103 | 0.1520 | -0.0016 |
MCF 10A | Mitoxantrone | 0.12 | uM | LJP6 | 72 | hr | 1694 | 1599 | 11217 | 0.1426 | -0.0211 |
MCF 10A | Mitoxantrone | 0.37 | uM | LJP5 | 72 | hr | 1694 | 1623 | 11103 | 0.1462 | -0.0156 |
MCF 10A | Mitoxantrone | 0.37 | uM | LJP6 | 72 | hr | 1694 | 1479 | 11217 | 0.1319 | -0.0487 |
MCF 10A | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 1694 | 1422 | 11103 | 0.1281 | -0.0630 |
MCF 10A | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 1694 | 1380 | 11217 | 0.1231 | -0.0724 |
MCF 10A | Mitoxantrone | 3.33 | uM | LJP5 | 72 | hr | 1694 | 775 | 11103 | 0.0699 | -0.2510 |
MCF 10A | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 1694 | 630 | 11217 | 0.0562 | -0.3070 |
MCF 10A | Mitoxantrone | 10 | uM | LJP5 | 72 | hr | 1694 | 992 | 11103 | 0.0893 | -0.1791 |
MCF 10A | Mitoxantrone | 10 | uM | LJP6 | 72 | hr | 1694 | 697 | 11217 | 0.0621 | -0.2789 |
MCF 10A | Radicicol | 0.04 | uM | LJP5 | 72 | hr | 1694 | 9940 | 11103 | 0.8953 | 0.9201 |
MCF 10A | Radicicol | 0.04 | uM | LJP6 | 72 | hr | 1694 | 9703 | 11217 | 0.8651 | 0.8964 |
MCF 10A | Radicicol | 0.12 | uM | LJP5 | 72 | hr | 1694 | 7622 | 11103 | 0.6865 | 0.7409 |
MCF 10A | Radicicol | 0.12 | uM | LJP6 | 72 | hr | 1694 | 7232 | 11217 | 0.6445 | 0.7018 |
MCF 10A | Radicicol | 0.37 | uM | LJP5 | 72 | hr | 1694 | 4503 | 11103 | 0.4057 | 0.4337 |
MCF 10A | Radicicol | 0.37 | uM | LJP6 | 72 | hr | 1694 | 4177 | 11217 | 0.3722 | 0.3911 |
MCF 10A | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2365 | 11103 | 0.2131 | 0.1302 |
MCF 10A | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 1694 | 2358 | 11217 | 0.2102 | 0.1276 |
MCF 10A | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 1694 | 1519 | 11103 | 0.1368 | -0.0414 |