LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Buparlisib
0.04
uM
LJP5
 72
hr
 765 2958 3148 0.9396 0.9399
Hs 578T Buparlisib
0.12
uM
LJP5
 72
hr
 765 2597 3148 0.8249 0.8199
Hs 578T Buparlisib
0.37
uM
LJP5
 72
hr
 765 2123 3148 0.6743 0.6487
Hs 578T Buparlisib
1.11
uM
LJP5
 72
hr
 765 698 3148 0.2219 -0.0455
Hs 578T Buparlisib
3.33
uM
LJP5
 72
hr
 765 388 3148 0.1232 -0.2835
Hs 578T Buparlisib
10
uM
LJP5
 72
hr
 765 331 3148 0.1051 -0.3367
Hs 578T XL147
0.04
uM
LJP5
 72
hr
 765 3060 3148 0.9720 0.9722
Hs 578T XL147
0.12
uM
LJP5
 72
hr
 765 3068 3148 0.9748 0.9750
Hs 578T XL147
0.37
uM
LJP5
 72
hr
 765 3091 3148 0.9820 0.9822
Hs 578T XL147
1.11
uM
LJP5
 72
hr
 765 3041 3148 0.9662 0.9665
Hs 578T XL147
3.33
uM
LJP5
 72
hr
 765 2876 3148 0.9138 0.9136
Hs 578T XL147
10
uM
LJP5
 72
hr
 765 2579 3148 0.8192 0.8138
Hs 578T Y39983
0.04
uM
LJP6
 72
hr
 765 2784 3101 0.8978 0.8957
Hs 578T Y39983
0.12
uM
LJP6
 72
hr
 765 2537 3101 0.8179 0.8105
Hs 578T Y39983
0.37
uM
LJP6
 72
hr
 765 2484 3101 0.8011 0.7911
Hs 578T Y39983
1.11
uM
LJP6
 72
hr
 765 2320 3101 0.7483 0.7325
Hs 578T Y39983
3.33
uM
LJP6
 72
hr
 765 2018 3101 0.6508 0.6167
Hs 578T Y39983
10
uM
LJP6
 72
hr
 765 740 3101 0.2389 -0.0166
Hs 578T Nintedanib
0.04
uM
LJP6
 72
hr
 765 2816 3101 0.9079 0.9065
Hs 578T Nintedanib
0.12
uM
LJP6
 72
hr
 765 2668 3101 0.8602 0.8562
Hs 578T Nintedanib
0.37
uM
LJP6
 72
hr
 765 2285 3101 0.7367 0.7191
Hs 578T Nintedanib
1.11
uM
LJP6
 72
hr
 765 2180 3101 0.7029 0.6796
Hs 578T Nintedanib
3.33
uM
LJP6
 72
hr
 765 1601 3101 0.5172 0.4370
Hs 578T Nintedanib
10
uM
LJP6
 72
hr
 765 1168 3101 0.3764 0.2315
Hs 578T Foretinib
0.04
uM
LJP5
 72
hr
 765 2808 3148 0.8922 0.8913