LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Foretinib
0.12
uM
LJP5
 72
hr
 765 2665 3148 0.8466 0.8431
Hs 578T Foretinib
0.37
uM
LJP5
 72
hr
 765 1295 3148 0.4115 0.2936
Hs 578T Foretinib
1.11
uM
LJP5
 72
hr
 765 951 3148 0.3023 0.1125
Hs 578T Foretinib
3.33
uM
LJP5
 72
hr
 765 796 3148 0.2530 0.0198
Hs 578T Foretinib
10
uM
LJP5
 72
hr
 765 302 3148 0.0959 -0.3659
Hs 578T AZD 5438
0.04
uM
LJP6
 72
hr
 765 2937 3101 0.9467 0.9462
Hs 578T AZD 5438
0.12
uM
LJP6
 72
hr
 765 2334 3101 0.7522 0.7362
Hs 578T AZD 5438
0.37
uM
LJP6
 72
hr
 765 1360 3101 0.4383 0.3292
Hs 578T AZD 5438
1.11
uM
LJP6
 72
hr
 765 728 3101 0.2348 -0.0241
Hs 578T AZD 5438
3.33
uM
LJP6
 72
hr
 765 522 3101 0.1685 -0.1720
Hs 578T AZD 5438
10
uM
LJP6
 72
hr
 765 401 3101 0.1294 -0.2743
Hs 578T Pelitinib
0.04
uM
LJP5
 72
hr
 765 3131 3148 0.9947 0.9948
Hs 578T Pelitinib
0.12
uM
LJP5
 72
hr
 765 3111 3148 0.9883 0.9885
Hs 578T Pelitinib
0.37
uM
LJP5
 72
hr
 765 2616 3148 0.8312 0.8267
Hs 578T Pelitinib
1.11
uM
LJP5
 72
hr
 765 2396 3148 0.7611 0.7496
Hs 578T Pelitinib
3.33
uM
LJP5
 72
hr
 765 2021 3148 0.6420 0.6000
Hs 578T Pelitinib
10
uM
LJP5
 72
hr
 765 628 3148 0.1996 -0.0922
Hs 578T Luminespib
0.04
uM
LJP5
 72
hr
 765 690 3148 0.2192 -0.0500
Hs 578T Luminespib
0.12
uM
LJP5
 72
hr
 765 676 3148 0.2148 -0.0592
Hs 578T Luminespib
0.37
uM
LJP5
 72
hr
 765 664 3148 0.2111 -0.0667
Hs 578T Luminespib
1.11
uM
LJP5
 72
hr
 765 700 3148 0.2224 -0.0432
Hs 578T Luminespib
3.33
uM
LJP5
 72
hr
 765 649 3148 0.2062 -0.0777
Hs 578T Luminespib
10
uM
LJP5
 72
hr
 765 690 3148 0.2193 -0.0496
Hs 578T AZD8330
0.04
uM
LJP5
 72
hr
 765 1146 3148 0.3642 0.2187
Hs 578T AZD8330
0.12
uM
LJP5
 72
hr
 765 1054 3148 0.3350 0.1703