LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Ruxolitinib
10
uM
LJP5
 72
hr
 765 2151 3148 0.6833 0.6594
Hs 578T Momelotinib
0.04
uM
LJP5
 72
hr
 765 2980 3148 0.9468 0.9471
Hs 578T Momelotinib
0.12
uM
LJP5
 72
hr
 765 2751 3148 0.8740 0.8722
Hs 578T Momelotinib
0.37
uM
LJP5
 72
hr
 765 2507 3148 0.7965 0.7888
Hs 578T Momelotinib
1.11
uM
LJP5
 72
hr
 765 2178 3148 0.6920 0.6695
Hs 578T Momelotinib
3.33
uM
LJP5
 72
hr
 765 1850 3148 0.5877 0.5413
Hs 578T Momelotinib
10
uM
LJP5
 72
hr
 765 754 3148 0.2395 -0.0071
Hs 578T Fedratinib
0.04
uM
LJP5
 72
hr
 765 3204 3148 1.0177 1.0170
Hs 578T Fedratinib
0.12
uM
LJP5
 72
hr
 765 3148 3148 1.0000 0.9999
Hs 578T Fedratinib
0.37
uM
LJP5
 72
hr
 765 2853 3148 0.9063 0.9057
Hs 578T Fedratinib
1.11
uM
LJP5
 72
hr
 765 2156 3148 0.6851 0.6616
Hs 578T Fedratinib
3.33
uM
LJP5
 72
hr
 765 1001 3148 0.3180 0.1407
Hs 578T Fedratinib
10
uM
LJP5
 72
hr
 765 321 3148 0.1021 -0.3478
Hs 578T Trametinib
0.04
uM
LJP5
 72
hr
 765 1192 3148 0.3787 0.2428
Hs 578T Trametinib
0.12
uM
LJP5
 72
hr
 765 1051 3148 0.3338 0.1682
Hs 578T Trametinib
0.37
uM
LJP5
 72
hr
 765 1038 3148 0.3298 0.1613
Hs 578T Trametinib
1.11
uM
LJP5
 72
hr
 765 975 3148 0.3097 0.1260
Hs 578T Trametinib
3.33
uM
LJP5
 72
hr
 765 1001 3148 0.3182 0.1410
Hs 578T Trametinib
10
uM
LJP5
 72
hr
 765 1000 3148 0.3176 0.1402
Hs 578T Omipalisib
0.04
uM
LJP6
 72
hr
 765 981 3101 0.3167 0.1313
Hs 578T Omipalisib
0.12
uM
LJP6
 72
hr
 765 720 3101 0.2325 -0.0316
Hs 578T Omipalisib
0.37
uM
LJP6
 72
hr
 765 573 3101 0.1850 -0.1329
Hs 578T Omipalisib
1.11
uM
LJP6
 72
hr
 765 470 3101 0.1517 -0.2157
Hs 578T Omipalisib
3.33
uM
LJP6
 72
hr
 765 405 3101 0.1308 -0.2708
Hs 578T Omipalisib
10
uM
LJP6
 72
hr
 765 358 3101 0.1157 -0.3151