LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Brivanib
0.37
uM
LJP5
 72
hr
 1694 10776 11103 0.9705 0.9781
MCF 10A Brivanib
0.12
uM
LJP5
 72
hr
 1694 10774 11103 0.9704 0.9779
MCF 10A Brivanib
0.04
uM
LJP5
 72
hr
 1694 11133 11103 1.0027 1.0020
Hs 578T Brivanib
0.37
uM
LJP5
 72
hr
 765 3069 3148 0.9750 0.9751
BT-20 Buparlisib
0.12
uM
LJP5
 72
hr
 1334 3831 4033 0.9506 0.9379
BT-20 Buparlisib
0.37
uM
LJP5
 72
hr
 1334 2698 4033 0.6696 0.5555
Hs 578T Buparlisib
0.37
uM
LJP5
 72
hr
 765 2123 3148 0.6743 0.6487
Hs 578T Buparlisib
1.11
uM
LJP5
 72
hr
 765 698 3148 0.2219 -0.0455
Hs 578T Buparlisib
0.12
uM
LJP5
 72
hr
 765 2597 3148 0.8249 0.8199
Hs 578T Buparlisib
3.33
uM
LJP5
 72
hr
 765 388 3148 0.1232 -0.2835
BT-20 Buparlisib
0.04
uM
LJP5
 72
hr
 1334 4150 4033 1.0287 1.0355
BT-20 Buparlisib
1.11
uM
LJP5
 72
hr
 1334 1273 4033 0.3157 -0.0294
Hs 578T Buparlisib
10
uM
LJP5
 72
hr
 765 331 3148 0.1051 -0.3367
BT-20 Buparlisib
3.33
uM
LJP5
 72
hr
 1334 612 4033 0.1519 -0.3867
Hs 578T Buparlisib
0.04
uM
LJP5
 72
hr
 765 2958 3148 0.9396 0.9399
BT-20 Buparlisib
10
uM
LJP5
 72
hr
 1334 463 4033 0.1148 -0.4855
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 72
hr
 1311 4524 5079 0.8907 0.8849
MDA-MB-231 Buparlisib
1.11
uM
LJP5
 72
hr
 1311 2763 5079 0.5439 0.4643
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 72
hr
 1311 4960 5079 0.9767 0.9761
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 72
hr
 1311 1607 5079 0.3163 0.1090
SK-BR-3 Buparlisib
0.04
uM
LJP5
 72
hr
 2543 5577 5752 0.9696 0.9479
SK-BR-3 Buparlisib
10
uM
LJP5
 72
hr
 2543 1222 5752 0.2125 -0.4633
MDA-MB-231 Buparlisib
10
uM
LJP5
 72
hr
 1311 735 5079 0.1447 -0.2566
SK-BR-3 Buparlisib
0.37
uM
LJP5
 72
hr
 2543 2940 5752 0.5110 0.1305
SK-BR-3 Buparlisib
0.12
uM
LJP5
 72
hr
 2543 4773 5752 0.8299 0.7071