LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Mitoxantrone
0.37
uM
LJP5
 72
hr
 765 628 3148 0.1995 -0.0923
Hs 578T Pelitinib
10
uM
LJP5
 72
hr
 765 628 3148 0.1996 -0.0922
MCF 10A Mitoxantrone
3.33
uM
LJP6
 72
hr
 1694 630 11217 0.0562 -0.3070
BT-20 Torin2
3.33
uM
LJP5
 72
hr
 1334 631 4033 0.1566 -0.3746
Hs 578T HG-5-113-01
10
uM
LJP5
 72
hr
 765 631 3148 0.2006 -0.0900
Hs 578T AZD7762
0.12
uM
LJP6
 72
hr
 765 632 3101 0.2040 -0.0903
MDA-MB-231 LDN-193189
10
uM
LJP5
 72
hr
 1311 641 5079 0.1260 -0.3126
MDA-MB-231 Fedratinib
10
uM
LJP5
 72
hr
 1311 642 5079 0.1263 -0.3080
Hs 578T PD0325901
10
uM
LJP5
 72
hr
 765 643 3148 0.2045 -0.0817
BT-20 Mitoxantrone
1.11
uM
LJP6
 72
hr
 1334 645 3925 0.1646 -0.3742
Hs 578T R406
10
uM
LJP6
 72
hr
 765 646 3101 0.2084 -0.0805
BT-20 Withaferin A
3.33
uM
LJP5
 72
hr
 1334 647 4033 0.1605 -0.3650
Hs 578T NVP-AEW541
10
uM
LJP5
 72
hr
 765 647 3148 0.2055 -0.0789
BT-20 GW843682X
10
uM
LJP6
 72
hr
 1334 648 3925 0.1652 -0.3713
Hs 578T Luminespib
3.33
uM
LJP5
 72
hr
 765 649 3148 0.2062 -0.0777
MDA-MB-231 AZD 5438
10
uM
LJP6
 72
hr
 1311 652 4935 0.1322 -0.3061
Hs 578T WYE-125132
10
uM
LJP6
 72
hr
 765 658 3101 0.2124 -0.0717
MCF7 CGP60474
0.12
uM
LJP6
 72
hr
 1389 659 5445 0.1217 -0.3150
Hs 578T Mitoxantrone
0.37
uM
LJP6
 72
hr
 765 661 3101 0.2132 -0.0696
Hs 578T Crizotinib
10
uM
LJP5
 72
hr
 765 662 3148 0.2103 -0.0696
Hs 578T Nilotinib
10
uM
LJP5
 72
hr
 765 662 3148 0.2105 -0.0684
Hs 578T Luminespib
0.37
uM
LJP5
 72
hr
 765 664 3148 0.2111 -0.0667
MCF7 PF431396
10
uM
LJP5
 72
hr
 1389 665 5905 0.1127 -0.2973
BT-20 Torin2
10
uM
LJP5
 72
hr
 1334 667 4033 0.1658 -0.3523
Hs 578T Mitoxantrone
0.12
uM
LJP6
 72
hr
 765 669 3101 0.2156 -0.0645