LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
SK-BR-3 CGP60474
3.33
uM
LJP6
 72
hr
 2543 1058 5418 0.1952 -0.5529
MDA-MB-231 Luminespib
10
uM
LJP5
 72
hr
 1311 992 5079 0.1953 -0.1334
MDA-MB-231 Luminespib
0.12
uM
LJP5
 72
hr
 1311 993 5079 0.1956 -0.1327
MCF 10A Torin2
3.33
uM
LJP5
 72
hr
 1694 2174 11103 0.1959 0.0961
BT-20 BI-2536
3.33
uM
LJP6
 72
hr
 1334 769 3925 0.1959 -0.2984
BT-20 Withaferin A
10
uM
LJP6
 72
hr
 1334 771 3925 0.1963 -0.2993
MCF7 QL-XII-47
10
uM
LJP6
 72
hr
 1389 1074 5445 0.1966 -0.1261
MCF7 GSK1059615
10
uM
LJP5
 72
hr
 1389 1167 5905 0.1974 -0.0811
BT-20 Geldanamycin
10
uM
LJP5
 72
hr
 1334 796 4033 0.1974 -0.2775
MCF7 Buparlisib
1.11
uM
LJP5
 72
hr
 1389 1167 5905 0.1975 -0.0810
MCF 10A XMD16-144
0.37
uM
LJP5
 72
hr
 1694 2195 11103 0.1977 0.1000
MCF7 Dasatinib
10
uM
LJP5
 72
hr
 1389 1168 5905 0.1977 -0.0803
SK-BR-3 CGP60474
3.33
uM
LJP5
 72
hr
 2543 1140 5752 0.1982 -0.4943
MCF 10A PI103
10
uM
LJP6
 72
hr
 1694 2227 11217 0.1985 0.1048
MCF7 Omipalisib
3.33
uM
LJP6
 72
hr
 1389 1081 5445 0.1986 -0.1204
MDA-MB-231 Mitoxantrone
0.37
uM
LJP5
 72
hr
 1311 1009 5079 0.1987 -0.1258
MCF 10A Canertinib
3.33
uM
LJP6
 72
hr
 1694 2228 11217 0.1987 0.1055
BT-20 Torin2
1.11
uM
LJP5
 72
hr
 1334 801 4033 0.1989 -0.2736
MCF 10A Omipalisib
0.04
uM
LJP6
 72
hr
 1694 2233 11217 0.1990 0.1064
SK-BR-3 SNS-032
3.33
uM
LJP6
 72
hr
 2543 1077 5418 0.1991 -0.5453
BT-20 CGP60474
0.04
uM
LJP6
 72
hr
 1334 782 3925 0.1992 -0.2908
SK-BR-3 PF562271
10
uM
LJP6
 72
hr
 2543 1079 5418 0.1994 -0.5446
Hs 578T Celastrol
3.33
uM
LJP6
 72
hr
 765 618 3101 0.1994 -0.1008
BT-20 Dasatinib
10
uM
LJP6
 72
hr
 1334 781 3925 0.1994 -0.2940
SK-BR-3 TWS119
10
uM
LJP5
 72
hr
 2543 1147 5752 0.1994 -0.4923