LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A CGP60474
10
uM
LJP6
 72
hr
 1694 439 11217 0.0391 -0.3938
MCF 10A SNS-032
0.37
uM
LJP6
 72
hr
 1694 464 11217 0.0414 -0.3793
MCF 10A CGP60474
3.33
uM
LJP5
 72
hr
 1694 466 11103 0.0420 -0.3789
MCF 10A Withaferin A
3.33
uM
LJP5
 72
hr
 1694 480 11103 0.0432 -0.3722
MCF 10A PF562271
10
uM
LJP6
 72
hr
 1694 494 11217 0.0440 -0.3639
MCF 10A CGP60474
10
uM
LJP5
 72
hr
 1694 500 11103 0.0451 -0.3665
MCF 10A AZD 5438
3.33
uM
LJP6
 72
hr
 1694 513 11217 0.0457 -0.3571
MCF 10A A443654
10
uM
LJP6
 72
hr
 1694 538 11217 0.0480 -0.3439
MCF 10A PHA-793887
10
uM
LJP6
 72
hr
 1694 558 11217 0.0498 -0.3347
MCF7 Mitoxantrone
10
uM
LJP5
 72
hr
 1389 296 5905 0.0502 -0.5229
MCF 10A JNK-9L
3.33
uM
LJP6
 72
hr
 1694 575 11217 0.0512 -0.3276
MCF 10A AZD 5438
10
uM
LJP6
 72
hr
 1694 574 11217 0.0512 -0.3275
MCF 10A Radicicol
10
uM
LJP5
 72
hr
 1694 602 11103 0.0543 -0.3171
MCF 10A Alvocidib
0.12
uM
LJP6
 72
hr
 1694 610 11217 0.0545 -0.3126
SK-BR-3 Mitoxantrone
10
uM
LJP6
 72
hr
 2543 295 5418 0.0546 -0.8617
Hs 578T Mitoxantrone
10
uM
LJP5
 72
hr
 765 172 3148 0.0546 -0.5188
MCF7 AZD 5438
10
uM
LJP6
 72
hr
 1389 297 5445 0.0548 -0.5439
MCF7 CGP60474
10
uM
LJP6
 72
hr
 1389 300 5445 0.0552 -0.5407
MCF 10A Buparlisib
10
uM
LJP5
 72
hr
 1694 615 11103 0.0554 -0.3121
MCF 10A AT-7519
1.11
uM
LJP6
 72
hr
 1694 623 11217 0.0556 -0.3072
MCF 10A Mitoxantrone
3.33
uM
LJP6
 72
hr
 1694 630 11217 0.0562 -0.3070
Hs 578T HG-6-64-01
10
uM
LJP6
 72
hr
 765 174 3101 0.0564 -0.5216
MCF7 CGP60474
10
uM
LJP5
 72
hr
 1389 343 5905 0.0581 -0.4884
BT-20 A443654
10
uM
LJP6
 72
hr
 1334 232 3925 0.0593 -0.6746
Hs 578T Mitoxantrone
3.33
uM
LJP5
 72
hr
 765 189 3148 0.0601 -0.4956