LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T SNS-032
0.37
uM
LJP6
 72
hr
 765 422 3101 0.1361 -0.2552
Hs 578T CGP60474
0.37
uM
LJP6
 72
hr
 765 422 3101 0.1362 -0.2549
SK-BR-3 CGP60474
10
uM
LJP6
 72
hr
 2543 739 5418 0.1364 -0.6782
MCF7 Omipalisib
10
uM
LJP6
 72
hr
 1389 746 5445 0.1367 -0.2743
MCF 10A Radicicol
3.33
uM
LJP5
 72
hr
 1694 1519 11103 0.1368 -0.0414
MDA-MB-231 Dasatinib
10
uM
LJP6
 72
hr
 1311 677 4935 0.1373 -0.2930
MDA-MB-231 Alvocidib
10
uM
LJP6
 72
hr
 1311 680 4935 0.1379 -0.2909
MDA-MB-231 CGP60474
1.11
uM
LJP6
 72
hr
 1311 680 4935 0.1379 -0.2907
MCF7 Afatinib
10
uM
LJP6
 72
hr
 1389 760 5445 0.1389 -0.2677
Hs 578T SNS-032
3.33
uM
LJP6
 72
hr
 765 431 3101 0.1389 -0.2475
MCF7 AT-7519
0.37
uM
LJP6
 72
hr
 1389 755 5445 0.1389 -0.2665
Hs 578T Mitoxantrone
1.11
uM
LJP6
 72
hr
 765 434 3101 0.1399 -0.2450
Hs 578T Alvocidib
0.12
uM
LJP6
 72
hr
 765 434 3101 0.1403 -0.2454
MCF 10A PHA-793887
3.33
uM
LJP6
 72
hr
 1694 1580 11217 0.1408 -0.0259
MCF7 AZD7762
10
uM
LJP6
 72
hr
 1389 771 5445 0.1412 -0.2608
BT-20 PF431396
10
uM
LJP5
 72
hr
 1334 571 4033 0.1415 -0.4131
MDA-MB-231 Canertinib
10
uM
LJP6
 72
hr
 1311 699 4935 0.1417 -0.2806
Hs 578T PF477736
10
uM
LJP5
 72
hr
 765 446 3148 0.1419 -0.2320
Hs 578T BI-2536
0.04
uM
LJP6
 72
hr
 765 440 3101 0.1420 -0.2401
Hs 578T WZ3105
0.37
uM
LJP5
 72
hr
 765 447 3148 0.1421 -0.2312
Hs 578T Mitoxantrone
1.11
uM
LJP5
 72
hr
 765 448 3148 0.1424 -0.2309
MCF 10A Mitoxantrone
0.12
uM
LJP6
 72
hr
 1694 1599 11217 0.1426 -0.0211
Hs 578T GW843682X
1.11
uM
LJP6
 72
hr
 765 442 3101 0.1428 -0.2374
MCF7 Buparlisib
10
uM
LJP5
 72
hr
 1389 844 5905 0.1430 -0.2124
Hs 578T WH-4-025
1.11
uM
LJP5
 72
hr
 765 450 3148 0.1431 -0.2298