LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Dasatinib
3.33
uM
LJP5
 72
hr
 765 482 3148 0.1531 -0.2040
MCF 10A WZ3105
0.37
uM
LJP5
 72
hr
 1694 916 11103 0.0825 -0.2039
SK-BR-3 Canertinib
0.37
uM
LJP6
 72
hr
 2543 1983 5418 0.3664 -0.2038
MCF 10A Geldanamycin
10
uM
LJP5
 72
hr
 1694 925 11103 0.0833 -0.2033
MDA-MB-231 PHA-665752
10
uM
LJP5
 72
hr
 1311 844 5079 0.1662 -0.2026
Hs 578T WZ3105
0.04
uM
LJP5
 72
hr
 765 483 3148 0.1534 -0.2022
MCF7 HG-6-64-01
10
uM
LJP6
 72
hr
 1389 896 5445 0.1651 -0.1996
MCF 10A Omipalisib
10
uM
LJP6
 72
hr
 1694 925 11217 0.0825 -0.1994
Hs 578T Afatinib
10
uM
LJP6
 72
hr
 765 491 3101 0.1583 -0.1974
Hs 578T PF431396
10
uM
LJP5
 72
hr
 765 489 3148 0.1554 -0.1970
BT-20 Mitoxantrone
0.37
uM
LJP6
 72
hr
 1334 954 3925 0.2432 -0.1966
MDA-MB-231 Alvocidib
0.12
uM
LJP6
 72
hr
 1311 866 4935 0.1756 -0.1954
BT-20 Luminespib
0.12
uM
LJP5
 72
hr
 1334 945 4033 0.2344 -0.1947
SK-BR-3 Tozasertib
0.12
uM
LJP5
 72
hr
 2543 1972 5752 0.3429 -0.1943
SK-BR-3 Tozasertib
3.33
uM
LJP5
 72
hr
 2543 1973 5752 0.3430 -0.1941
MDA-MB-231 WZ3105
0.04
uM
LJP5
 72
hr
 1311 862 5079 0.1699 -0.1937
SK-BR-3 AZD8055
0.04
uM
LJP6
 72
hr
 2543 2013 5418 0.3717 -0.1933
BT-20 Luminespib
0.37
uM
LJP5
 72
hr
 1334 949 4033 0.2352 -0.1930
MCF7 BI-2536
10
uM
LJP6
 72
hr
 1389 912 5445 0.1676 -0.1930
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 72
hr
 1311 874 4935 0.1771 -0.1925
MCF7 Buparlisib
3.33
uM
LJP5
 72
hr
 1389 890 5905 0.1508 -0.1921
Hs 578T AZD7762
1.11
uM
LJP6
 72
hr
 765 497 3101 0.1604 -0.1920
Hs 578T Torin2
3.33
uM
LJP5
 72
hr
 765 495 3148 0.1574 -0.1919
MDA-MB-231 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1311 865 5079 0.1705 -0.1917
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 72
hr
 1311 874 4935 0.1773 -0.1913