LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T SB590885
0.12
uM
LJP5
72
hr
765 3734 3148 1.1863 1.1744
Hs 578T PLX-4720
1.11
uM
LJP5
72
hr
765 3735 3148 1.1865 1.1747
SK-BR-3 Nilotinib
0.37
uM
LJP5
72
hr
2543 6352 5752 1.1044 1.1760
Hs 578T SB590885
0.37
uM
LJP5
72
hr
765 3748 3148 1.1907 1.1785
Hs 578T PLX-4720
0.37
uM
LJP5
72
hr
765 3751 3148 1.1915 1.1790
MCF7 HG-6-64-01
0.04
uM
LJP6
72
hr
1389 6450 5445 1.1889 1.1853
SK-BR-3 HG-6-64-01
0.12
uM
LJP6
72
hr
2543 5967 5418 1.1017 1.1866
Hs 578T SB590885
1.11
uM
LJP5
72
hr
765 3789 3148 1.2038 1.1903
Hs 578T SB590885
0.04
uM
LJP5
72
hr
765 3790 3148 1.2041 1.1904
BT-20 Enzastaurin
10
uM
LJP5
72
hr
1334 4675 4033 1.1588 1.1931
Hs 578T Sorafenib
0.37
uM
LJP6
72
hr
765 3768 3101 1.2151 1.2026
Hs 578T Sorafenib
3.33
uM
LJP6
72
hr
765 3770 3101 1.2154 1.2028
Hs 578T SB590885
3.33
uM
LJP5
72
hr
765 3864 3148 1.2276 1.2113
Hs 578T Sorafenib
1.11
uM
LJP6
72
hr
765 3829 3101 1.2349 1.2203
SK-BR-3 HG-6-64-01
0.04
uM
LJP6
72
hr
2543 6137 5418 1.1335 1.2457