LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1573 | 5752 | 0.2735 | -0.3354 |
| BT-20 | Mitoxantrone | 3.33 | uM | LJP5 | 72 | hr | 1334 | 698 | 4033 | 0.1729 | -0.3347 |
| MCF 10A | PHA-793887 | 10 | uM | LJP6 | 72 | hr | 1694 | 558 | 11217 | 0.0498 | -0.3347 |
| SK-BR-3 | PF477736 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 1575 | 5752 | 0.2738 | -0.3345 |
| SK-BR-3 | Geldanamycin | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1576 | 5752 | 0.2740 | -0.3344 |
| SK-BR-3 | Pelitinib | 10 | uM | LJP5 | 72 | hr | 2543 | 1578 | 5752 | 0.2743 | -0.3334 |
| MDA-MB-231 | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 606 | 4935 | 0.1231 | -0.3331 |
| SK-BR-3 | Torin1 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1639 | 5418 | 0.3028 | -0.3316 |
| BT-20 | BI-2536 | 10 | uM | LJP6 | 72 | hr | 1334 | 716 | 3925 | 0.1825 | -0.3297 |
| MDA-MB-231 | AT-7519 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 613 | 4935 | 0.1243 | -0.3284 |
| BT-20 | Withaferin A | 1.11 | uM | LJP5 | 72 | hr | 1334 | 708 | 4033 | 0.1760 | -0.3277 |
| MCF 10A | JNK-9L | 3.33 | uM | LJP6 | 72 | hr | 1694 | 575 | 11217 | 0.0512 | -0.3276 |
| MCF 10A | AZD 5438 | 10 | uM | LJP6 | 72 | hr | 1694 | 574 | 11217 | 0.0512 | -0.3275 |
| Hs 578T | Geldanamycin | 10 | uM | LJP5 | 72 | hr | 765 | 344 | 3148 | 0.1095 | -0.3253 |
| Hs 578T | CGP60474 | 0.04 | uM | LJP6 | 72 | hr | 765 | 346 | 3101 | 0.1119 | -0.3251 |
| MCF7 | WZ3105 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 614 | 5905 | 0.1040 | -0.3239 |
| SK-BR-3 | SB590885 | 10 | uM | LJP5 | 72 | hr | 2543 | 1608 | 5752 | 0.2796 | -0.3226 |
| Hs 578T | BMS345541 | 10 | uM | LJP6 | 72 | hr | 765 | 349 | 3101 | 0.1125 | -0.3224 |
| MDA-MB-231 | CGP60474 | 10 | uM | LJP6 | 72 | hr | 1311 | 625 | 4935 | 0.1268 | -0.3224 |
| Hs 578T | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 765 | 349 | 3101 | 0.1126 | -0.3219 |
| BT-20 | Omipalisib | 1.11 | uM | LJP6 | 72 | hr | 1334 | 734 | 3925 | 0.1869 | -0.3208 |
| Hs 578T | Dasatinib | 10 | uM | LJP6 | 72 | hr | 765 | 354 | 3101 | 0.1144 | -0.3207 |
| MDA-MB-231 | Omipalisib | 10 | uM | LJP6 | 72 | hr | 1311 | 626 | 4935 | 0.1270 | -0.3207 |
| SK-BR-3 | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1616 | 5752 | 0.2810 | -0.3196 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP5 | 72 | hr | 1389 | 626 | 5905 | 0.1061 | -0.3172 |