LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1311 746 4935 0.1512 -0.2558
Hs 578T Torin1
10
uM
LJP6
 72
hr
 765 482 3101 0.1553 -0.2049
MDA-MB-231 Mitoxantrone
10
uM
LJP6
 72
hr
 1311 560 4935 0.1136 -0.3597
MCF 10A Afatinib
0.04
uM
LJP6
 72
hr
 1694 1726 11217 0.1540 0.0062
MDA-MB-231 Radicicol
0.04
uM
LJP6
 72
hr
 1311 5119 4935 1.0373 1.0387
MCF 10A CGP60474
0.04
uM
LJP6
 72
hr
 1694 387 11217 0.0345 -0.4189
MDA-MB-231 Radicicol
0.12
uM
LJP6
 72
hr
 1311 4328 4935 0.8771 0.8675
MCF 10A PD0325901
0.04
uM
LJP6
 72
hr
 1694 3467 11217 0.3092 0.3003
MDA-MB-231 Radicicol
0.37
uM
LJP6
 72
hr
 1311 2483 4935 0.5031 0.3960
MCF 10A CGP60474
0.12
uM
LJP6
 72
hr
 1694 306 11217 0.0273 -0.4672
MDA-MB-231 Radicicol
1.11
uM
LJP6
 72
hr
 1311 1606 4935 0.3257 0.1117
MCF 10A Afatinib
0.12
uM
LJP6
 72
hr
 1694 1655 11217 0.1476 -0.0089
MDA-MB-231 Radicicol
3.33
uM
LJP6
 72
hr
 1311 1216 4935 0.2464 -0.0390
MCF 10A CGP60474
0.37
uM
LJP6
 72
hr
 1694 364 11217 0.0325 -0.4327
MDA-MB-231 Radicicol
10
uM
LJP6
 72
hr
 1311 1256 4935 0.2545 -0.0227