LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 CGP60474
3.33
uM
LJP5
 72
hr
 1389 359 5905 0.0608 -0.4776
MCF7 HG-6-64-01
3.33
uM
LJP6
 72
hr
 1389 3449 5445 0.6335 0.5851
MCF7 Sorafenib
3.33
uM
LJP6
 72
hr
 1389 4391 5445 0.8027 0.7828
MCF7 Crizotinib
3.33
uM
LJP5
 72
hr
 1389 1744 5905 0.2934 0.0972
MCF7 WYE-125132
3.33
uM
LJP6
 72
hr
 1389 1701 5445 0.3129 0.1083
MCF7 Imatinib
3.33
uM
LJP6
 72
hr
 1389 5850 5445 1.0778 1.0789
MCF7 BMS345541
3.33
uM
LJP6
 72
hr
 1389 1593 5445 0.2926 0.0696
MCF7 AZD7762
3.33
uM
LJP6
 72
hr
 1389 1098 5445 0.2015 -0.1148
MCF7 CP466722
3.33
uM
LJP5
 72
hr
 1389 5916 5905 1.0023 1.0024
MCF7 GW843682X
3.33
uM
LJP6
 72
hr
 1389 1488 5445 0.2731 0.0338
MCF7 WH-4-025
3.33
uM
LJP5
 72
hr
 1389 1662 5905 0.2815 0.0896
MCF7 Neratinib
3.33
uM
LJP5
 72
hr
 1389 3216 5905 0.5449 0.4953
MCF7 Tozasertib
3.33
uM
LJP5
 72
hr
 1389 1530 5905 0.2591 0.0471
MCF7 Seliciclib
3.33
uM
LJP5
 72
hr
 1389 4844 5905 0.8197 0.8176
MCF7 CP724714
3.33
uM
LJP5
 72
hr
 1389 5059 5905 0.8573 0.8579
MCF7 SB590885
3.33
uM
LJP5
 72
hr
 1389 6498 5905 1.1011 1.0947
MCF7 Pictilisib
3.33
uM
LJP6
 72
hr
 1389 1289 5445 0.2364 -0.0391
MCF7 AT-7519
3.33
uM
LJP6
 72
hr
 1389 479 5445 0.0885 -0.4181
MCF7 HG-5-88-01
3.33
uM
LJP6
 72
hr
 1389 1909 5445 0.3509 0.1747
MCF7 AZD8055
3.33
uM
LJP6
 72
hr
 1389 1413 5445 0.2590 0.0062
MCF7 Alvocidib
3.33
uM
LJP6
 72
hr
 1389 468 5445 0.0859 -0.4251
MCF7 CGP60474
3.33
uM
LJP6
 72
hr
 1389 434 5445 0.0800 -0.4480
MCF7 Dasatinib
3.33
uM
LJP6
 72
hr
 1389 1046 5445 0.1919 -0.1358
MCF7 PF562271
3.33
uM
LJP6
 72
hr
 1389 1233 5445 0.2267 -0.0590
MCF7 Palbociclib
3.33
uM
LJP6
 72
hr
 1389 2633 5445 0.4835 0.3822