LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Radicicol
0.04
uM
LJP5
 72
hr
 1694 9940 11103 0.8953 0.9201
MCF 10A Pictilisib
0.04
uM
LJP6
 72
hr
 1694 9923 11217 0.8847 0.9120
MCF 10A Fedratinib
1.11
uM
LJP5
 72
hr
 1694 9912 11103 0.8928 0.9180
MCF 10A Withaferin A
0.37
uM
LJP5
 72
hr
 1694 9899 11103 0.8915 0.9171
MCF 10A GW843682X
0.12
uM
LJP6
 72
hr
 1694 9876 11217 0.8806 0.9089
MCF 10A GSK 690693
3.33
uM
LJP5
 72
hr
 1694 9870 11103 0.8890 0.9151
MCF 10A Withaferin A
0.37
uM
LJP6
 72
hr
 1694 9848 11217 0.8780 0.9067
MCF 10A AZD-6482
1.11
uM
LJP5
 72
hr
 1694 9840 11103 0.8862 0.9128
MCF 10A Crizotinib
1.11
uM
LJP5
 72
hr
 1694 9823 11103 0.8847 0.9116
MCF 10A GSK 690693
1.11
uM
LJP5
 72
hr
 1694 9787 11103 0.8815 0.9091
MCF 10A XL147
3.33
uM
LJP5
 72
hr
 1694 9760 11103 0.8790 0.9071
MCF 10A Linsitinib
0.12
uM
LJP5
 72
hr
 1694 9752 11103 0.8783 0.9066
MCF 10A Buparlisib
0.37
uM
LJP5
 72
hr
 1694 9711 11103 0.8746 0.9035
MCF 10A Radicicol
0.04
uM
LJP6
 72
hr
 1694 9703 11217 0.8651 0.8964
MCF 10A AZD 5438
0.12
uM
LJP6
 72
hr
 1694 9687 11217 0.8635 0.8951
MCF 10A Erlotinib
0.12
uM
LJP5
 72
hr
 1694 9664 11103 0.8704 0.9002
MCF 10A GSK1059615
0.12
uM
LJP6
 72
hr
 1694 9624 11217 0.8580 0.8908
MCF 10A HG-5-113-01
0.12
uM
LJP5
 72
hr
 1694 9608 11103 0.8654 0.8957
MCF 10A Lapatinib
1.11
uM
LJP6
 72
hr
 1694 9605 11217 0.8563 0.8894
MCF 10A Dovitinib
0.12
uM
LJP5
 72
hr
 1694 9580 11103 0.8627 0.8938
MCF 10A Alpelisib
0.37
uM
LJP5
 72
hr
 1694 9524 11103 0.8578 0.8900
MCF 10A XMD11-50
0.37
uM
LJP6
 72
hr
 1694 9518 11217 0.8486 0.8832
MCF 10A PF562271
0.04
uM
LJP6
 72
hr
 1694 9484 11217 0.8455 0.8806
MCF 10A PIK-93
3.33
uM
LJP5
 72
hr
 1694 9476 11103 0.8534 0.8864
MCF 10A Nintedanib
3.33
uM
LJP6
 72
hr
 1694 9454 11217 0.8429 0.8785