LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 CGP60474
10
uM
LJP6
 72
hr
 1389 300 5445 0.0552 -0.5407
MCF7 HG-5-88-01
0.37
uM
LJP6
 72
hr
 1389 3381 5445 0.6226 0.5710
MCF7 PD173074
0.04
uM
LJP6
 72
hr
 1389 6234 5445 1.1449 1.1423
MCF7 SNS-032
1.11
uM
LJP6
 72
hr
 1389 595 5445 0.1094 -0.3514
MCF7 PD173074
0.12
uM
LJP6
 72
hr
 1389 5836 5445 1.0737 1.0743
MCF7 HG-5-88-01
1.11
uM
LJP6
 72
hr
 1389 2672 5445 0.4902 0.3914
MCF7 PD173074
0.37
uM
LJP6
 72
hr
 1389 5549 5445 1.0189 1.0189
MCF7 OSI-027
0.04
uM
LJP6
 72
hr
 1389 5485 5445 1.0072 1.0073
MCF7 OSI-027
0.12
uM
LJP6
 72
hr
 1389 4017 5445 0.7386 0.7131
MCF7 OSI-027
0.37
uM
LJP6
 72
hr
 1389 2848 5445 0.5229 0.4382
MCF7 OSI-027
1.11
uM
LJP6
 72
hr
 1389 2175 5445 0.3993 0.2544
MCF7 OSI-027
3.33
uM
LJP6
 72
hr
 1389 2141 5445 0.3935 0.2451
MCF7 OSI-027
10
uM
LJP6
 72
hr
 1389 1894 5445 0.3486 0.1707
MCF7 WYE-125132
0.04
uM
LJP6
 72
hr
 1389 1958 5445 0.3614 0.1917
MCF7 WYE-125132
0.12
uM
LJP6
 72
hr
 1389 1919 5445 0.3532 0.1784
MCF7 WYE-125132
0.37
uM
LJP6
 72
hr
 1389 1854 5445 0.3416 0.1586
MCF7 WYE-125132
1.11
uM
LJP6
 72
hr
 1389 1894 5445 0.3490 0.1713
MCF7 WYE-125132
3.33
uM
LJP6
 72
hr
 1389 1701 5445 0.3129 0.1083
MCF7 WYE-125132
10
uM
LJP6
 72
hr
 1389 1652 5445 0.3039 0.0920
MCF7 Palbociclib
1.11
uM
LJP6
 72
hr
 1389 3058 5445 0.5622 0.4926
MCF7 HG-6-64-01
0.12
uM
LJP6
 72
hr
 1389 5981 5445 1.1007 1.1010
MCF7 PF562271
0.37
uM
LJP6
 72
hr
 1389 3527 5445 0.6477 0.6036
MCF7 AZD7762
3.33
uM
LJP6
 72
hr
 1389 1098 5445 0.2015 -0.1148
MCF7 PF562271
3.33
uM
LJP6
 72
hr
 1389 1233 5445 0.2267 -0.0590
MCF7 Afatinib
3.33
uM
LJP6
 72
hr
 1389 3759 5445 0.6907 0.6572