LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 PD184352
0.37
uM
LJP5
 72
hr
 1389 4444 5905 0.7520 0.7442
MCF7 PD184352
1.11
uM
LJP5
 72
hr
 1389 3827 5905 0.6477 0.6238
MCF7 PD184352
3.33
uM
LJP5
 72
hr
 1389 3553 5905 0.6029 0.5685
MCF7 PD184352
10
uM
LJP5
 72
hr
 1389 2750 5905 0.4653 0.3857
MCF7 PLX-4720
0.04
uM
LJP5
 72
hr
 1389 6242 5905 1.0572 1.0541
MCF7 PLX-4720
0.12
uM
LJP5
 72
hr
 1389 5721 5905 0.9689 0.9701
MCF7 PLX-4720
0.37
uM
LJP5
 72
hr
 1389 6284 5905 1.0634 1.0590
MCF7 PLX-4720
1.11
uM
LJP5
 72
hr
 1389 5989 5905 1.0147 1.0143
MCF7 PLX-4720
3.33
uM
LJP5
 72
hr
 1389 5426 5905 0.9189 0.9206
MCF7 PLX-4720
10
uM
LJP5
 72
hr
 1389 3091 5905 0.5230 0.4654
MCF7 Lapatinib
0.04
uM
LJP6
 72
hr
 1389 4859 5445 0.8951 0.8912
MCF7 Lapatinib
0.12
uM
LJP6
 72
hr
 1389 5503 5445 1.0138 1.0147
MCF7 Lapatinib
0.37
uM
LJP6
 72
hr
 1389 5614 5445 1.0316 1.0319
MCF7 Lapatinib
1.11
uM
LJP6
 72
hr
 1389 5610 5445 1.0319 1.0331
MCF7 Lapatinib
3.33
uM
LJP6
 72
hr
 1389 5083 5445 0.9368 0.9357
MCF7 Lapatinib
10
uM
LJP6
 72
hr
 1389 2624 5445 0.4818 0.3782
MCF7 Sirolimus
0.04
uM
LJP6
 72
hr
 1389 3193 5445 0.5886 0.5278
MCF7 Sirolimus
0.12
uM
LJP6
 72
hr
 1389 3177 5445 0.5840 0.5219
MCF7 Sirolimus
0.37
uM
LJP6
 72
hr
 1389 3167 5445 0.5826 0.5201
MCF7 Sirolimus
1.11
uM
LJP6
 72
hr
 1389 3115 5445 0.5726 0.5068
MCF7 Sirolimus
3.33
uM
LJP6
 72
hr
 1389 3196 5445 0.5878 0.5269
MCF7 Sirolimus
10
uM
LJP6
 72
hr
 1389 2978 5445 0.5475 0.4728
MCF7 ZSTK474
0.04
uM
LJP6
 72
hr
 1389 4300 5445 0.7900 0.7742
MCF7 ZSTK474
0.12
uM
LJP6
 72
hr
 1389 3157 5445 0.5788 0.5133
MCF7 ZSTK474
0.37
uM
LJP6
 72
hr
 1389 1922 5445 0.3542 0.1800