LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 ZSTK474
1.11
uM
LJP6
 72
hr
 1389 1689 5445 0.3108 0.1044
MCF7 ZSTK474
3.33
uM
LJP6
 72
hr
 1389 1571 5445 0.2888 0.0640
MCF7 ZSTK474
10
uM
LJP6
 72
hr
 1389 1515 5445 0.2791 0.0454
MCF7 BX-912
0.04
uM
LJP5
 72
hr
 1389 4745 5905 0.8033 0.8007
MCF7 BX-912
0.12
uM
LJP5
 72
hr
 1389 5484 5905 0.9298 0.9315
MCF7 BX-912
0.37
uM
LJP5
 72
hr
 1389 5266 5905 0.8911 0.8918
MCF7 BX-912
1.11
uM
LJP5
 72
hr
 1389 3569 5905 0.6040 0.5703
MCF7 BX-912
3.33
uM
LJP5
 72
hr
 1389 2637 5905 0.4465 0.3590
MCF7 BX-912
10
uM
LJP5
 72
hr
 1389 1535 5905 0.2600 0.0489
MCF7 Selumetinib
0.04
uM
LJP6
 72
hr
 1389 4868 5445 0.8954 0.8915
MCF7 Selumetinib
0.12
uM
LJP6
 72
hr
 1389 4127 5445 0.7573 0.7358
MCF7 Selumetinib
0.37
uM
LJP6
 72
hr
 1389 3295 5445 0.6065 0.5517
MCF7 Selumetinib
1.11
uM
LJP6
 72
hr
 1389 3004 5445 0.5530 0.4802
MCF7 Selumetinib
3.33
uM
LJP6
 72
hr
 1389 3098 5445 0.5695 0.5026
MCF7 Selumetinib
10
uM
LJP6
 72
hr
 1389 3071 5445 0.5671 0.4982
MCF7 MK2206
0.04
uM
LJP6
 72
hr
 1389 4071 5445 0.7484 0.7262
MCF7 MK2206
0.12
uM
LJP6
 72
hr
 1389 3511 5445 0.6447 0.5998
MCF7 MK2206
0.37
uM
LJP6
 72
hr
 1389 2368 5445 0.4350 0.3100
MCF7 MK2206
1.11
uM
LJP6
 72
hr
 1389 2765 5445 0.5086 0.4186
MCF7 MK2206
3.33
uM
LJP6
 72
hr
 1389 2211 5445 0.4065 0.2660
MCF7 MK2206
10
uM
LJP6
 72
hr
 1389 1453 5445 0.2667 0.0203
MCF7 AZD-6482
0.04
uM
LJP5
 72
hr
 1389 6084 5905 1.0297 1.0278
MCF7 AZD-6482
0.12
uM
LJP5
 72
hr
 1389 6014 5905 1.0180 1.0168
MCF7 AZD-6482
0.37
uM
LJP5
 72
hr
 1389 6318 5905 1.0688 1.0636
MCF7 AZD-6482
1.11
uM
LJP5
 72
hr
 1389 5388 5905 0.9123 0.9139