LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Dovitinib
0.12
uM
LJP5
 72
hr
 1389 5308 5905 0.8981 0.8988
MCF7 Dovitinib
0.37
uM
LJP5
 72
hr
 1389 4890 5905 0.8277 0.8263
MCF7 Dovitinib
1.11
uM
LJP5
 72
hr
 1389 4322 5905 0.7319 0.7222
MCF7 Dovitinib
3.33
uM
LJP5
 72
hr
 1389 3455 5905 0.5850 0.5469
MCF7 Dovitinib
10
uM
LJP5
 72
hr
 1389 2573 5905 0.4351 0.3413
MCF7 GSK 690693
0.04
uM
LJP5
 72
hr
 1389 4087 5905 0.6919 0.6763
MCF7 GSK 690693
0.12
uM
LJP5
 72
hr
 1389 4163 5905 0.7038 0.6883
MCF7 GSK 690693
0.37
uM
LJP5
 72
hr
 1389 3560 5905 0.6022 0.5678
MCF7 GSK 690693
1.11
uM
LJP5
 72
hr
 1389 3147 5905 0.5332 0.4798
MCF7 GSK 690693
3.33
uM
LJP5
 72
hr
 1389 2936 5905 0.4975 0.4314
MCF7 GSK 690693
10
uM
LJP5
 72
hr
 1389 2689 5905 0.4549 0.3704
MCF7 SNS-032
0.04
uM
LJP6
 72
hr
 1389 1491 5445 0.2737 0.0347
MCF7 SNS-032
0.12
uM
LJP6
 72
hr
 1389 679 5445 0.1248 -0.3060
MCF7 SNS-032
0.37
uM
LJP6
 72
hr
 1389 565 5445 0.1038 -0.3675
MCF7 SNS-032
1.11
uM
LJP6
 72
hr
 1389 595 5445 0.1094 -0.3514
MCF7 SNS-032
3.33
uM
LJP6
 72
hr
 1389 522 5445 0.0961 -0.3922
MCF7 SNS-032
10
uM
LJP6
 72
hr
 1389 444 5445 0.0814 -0.4409
MCF7 Afatinib
0.04
uM
LJP6
 72
hr
 1389 4541 5445 0.8383 0.8287
MCF7 Afatinib
0.12
uM
LJP6
 72
hr
 1389 4829 5445 0.8918 0.8866
MCF7 Afatinib
0.37
uM
LJP6
 72
hr
 1389 4933 5445 0.9071 0.9035
MCF7 Afatinib
1.11
uM
LJP6
 72
hr
 1389 4646 5445 0.8551 0.8471
MCF7 Afatinib
3.33
uM
LJP6
 72
hr
 1389 3759 5445 0.6907 0.6572
MCF7 Afatinib
10
uM
LJP6
 72
hr
 1389 760 5445 0.1389 -0.2677
MCF7 GSK1904529A
0.04
uM
LJP6
 72
hr
 1389 3648 5445 0.6718 0.6343
MCF7 GSK1904529A
0.12
uM
LJP6
 72
hr
 1389 3406 5445 0.6268 0.5778