LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Radicicol
0.37
uM
LJP5
 72
hr
 1311 2498 5079 0.4919 0.3898
MDA-MB-231 Radicicol
0.37
uM
LJP6
 72
hr
 1311 2483 4935 0.5031 0.3960
MDA-MB-231 Radicicol
1.11
uM
LJP5
 72
hr
 1311 1593 5079 0.3139 0.1044
MDA-MB-231 Radicicol
1.11
uM
LJP6
 72
hr
 1311 1606 4935 0.3257 0.1117
MDA-MB-231 Radicicol
3.33
uM
LJP5
 72
hr
 1311 1193 5079 0.2350 -0.0475
MDA-MB-231 Radicicol
3.33
uM
LJP6
 72
hr
 1311 1216 4935 0.2464 -0.0390
MDA-MB-231 Radicicol
10
uM
LJP5
 72
hr
 1311 1236 5079 0.2435 -0.0298
MDA-MB-231 Radicicol
10
uM
LJP6
 72
hr
 1311 1256 4935 0.2545 -0.0227
MDA-MB-231 Withaferin A
0.04
uM
LJP5
 72
hr
 1311 5106 5079 1.0052 1.0049
MDA-MB-231 Withaferin A
0.04
uM
LJP6
 72
hr
 1311 4878 4935 0.9882 0.9868
MDA-MB-231 Withaferin A
0.12
uM
LJP5
 72
hr
 1311 4805 5079 0.9462 0.9437
MDA-MB-231 Withaferin A
0.12
uM
LJP6
 72
hr
 1311 4866 4935 0.9862 0.9855
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 72
hr
 1311 4318 5079 0.8501 0.8402
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 72
hr
 1311 3880 4935 0.7865 0.7629
MDA-MB-231 Withaferin A
1.11
uM
LJP5
 72
hr
 1311 1384 5079 0.2728 0.0276
MDA-MB-231 Withaferin A
1.11
uM
LJP6
 72
hr
 1311 1295 4935 0.2626 -0.0068
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 72
hr
 1311 1037 5079 0.2043 -0.1133
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 72
hr
 1311 810 4935 0.1642 -0.2233
MDA-MB-231 Withaferin A
10
uM
LJP5
 72
hr
 1311 466 5079 0.0916 -0.4133
MDA-MB-231 Withaferin A
10
uM
LJP6
 72
hr
 1311 379 4935 0.0770 -0.4802
BT-20 Seliciclib
0.04
uM
LJP5
 72
hr
 1334 4094 4033 1.0156 1.0199
BT-20 Seliciclib
0.12
uM
LJP5
 72
hr
 1334 4007 4033 0.9941 0.9928
BT-20 Seliciclib
0.37
uM
LJP5
 72
hr
 1334 3825 4033 0.9490 0.9358
BT-20 Seliciclib
1.11
uM
LJP5
 72
hr
 1334 3827 4033 0.9489 0.9352
BT-20 Seliciclib
3.33
uM
LJP5
 72
hr
 1334 3442 4033 0.8529 0.8091