LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 72
hr
 1311 4882 5079 0.9612 0.9596
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 72
hr
 1311 4556 5079 0.8972 0.8920
MDA-MB-231 Alpelisib
10
uM
LJP5
 72
hr
 1311 3498 5079 0.6887 0.6523
MDA-MB-231 GDC-0980
0.04
uM
LJP5
 72
hr
 1311 4041 5079 0.7955 0.7789
MDA-MB-231 GDC-0980
0.12
uM
LJP5
 72
hr
 1311 3669 5079 0.7224 0.6933
MDA-MB-231 GDC-0980
0.37
uM
LJP5
 72
hr
 1311 2963 5079 0.5832 0.5173
MDA-MB-231 GDC-0980
1.11
uM
LJP5
 72
hr
 1311 2456 5079 0.4837 0.3788
MDA-MB-231 GDC-0980
3.33
uM
LJP5
 72
hr
 1311 2148 5079 0.4230 0.2874
MDA-MB-231 GDC-0980
10
uM
LJP5
 72
hr
 1311 1738 5079 0.3423 0.1552
MDA-MB-231 Mitoxantrone
0.04
uM
LJP5
 72
hr
 1311 1185 5079 0.2333 -0.0507
MDA-MB-231 Mitoxantrone
0.04
uM
LJP6
 72
hr
 1311 1081 4935 0.2192 -0.0969
MDA-MB-231 Mitoxantrone
0.12
uM
LJP5
 72
hr
 1311 1198 5079 0.2359 -0.0454
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 72
hr
 1311 1073 4935 0.2174 -0.1001
MDA-MB-231 Mitoxantrone
0.37
uM
LJP5
 72
hr
 1311 1009 5079 0.1987 -0.1258
MDA-MB-231 Mitoxantrone
0.37
uM
LJP6
 72
hr
 1311 992 4935 0.2011 -0.1359
MDA-MB-231 Mitoxantrone
1.11
uM
LJP5
 72
hr
 1311 968 5079 0.1906 -0.1440
MDA-MB-231 Mitoxantrone
1.11
uM
LJP6
 72
hr
 1311 904 4935 0.1833 -0.1770
MDA-MB-231 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1311 865 5079 0.1705 -0.1917
MDA-MB-231 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1311 746 4935 0.1512 -0.2558
MDA-MB-231 Mitoxantrone
10
uM
LJP5
 72
hr
 1311 786 5079 0.1548 -0.2306
MDA-MB-231 Mitoxantrone
10
uM
LJP6
 72
hr
 1311 560 4935 0.1136 -0.3597
MDA-MB-231 Radicicol
0.04
uM
LJP5
 72
hr
 1311 5349 5079 1.0531 1.0537
MDA-MB-231 Radicicol
0.04
uM
LJP6
 72
hr
 1311 5119 4935 1.0373 1.0387
MDA-MB-231 Radicicol
0.12
uM
LJP5
 72
hr
 1311 4268 5079 0.8404 0.8293
MDA-MB-231 Radicicol
0.12
uM
LJP6
 72
hr
 1311 4328 4935 0.8771 0.8675