LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 GW843682X
0.37
uM
LJP6
 72
hr
 1389 1883 5445 0.3463 0.1666
MCF7 GW843682X
1.11
uM
LJP6
 72
hr
 1389 1547 5445 0.2835 0.0527
MCF7 GW843682X
3.33
uM
LJP6
 72
hr
 1389 1488 5445 0.2731 0.0338
MCF7 GW843682X
10
uM
LJP6
 72
hr
 1389 1588 5445 0.2911 0.0675
MCF7 HG-5-113-01
0.04
uM
LJP5
 72
hr
 1389 5118 5905 0.8669 0.8678
MCF7 HG-5-113-01
0.12
uM
LJP5
 72
hr
 1389 4556 5905 0.7718 0.7667
MCF7 HG-5-113-01
0.37
uM
LJP5
 72
hr
 1389 3820 5905 0.6458 0.6201
MCF7 HG-5-113-01
1.11
uM
LJP5
 72
hr
 1389 2373 5905 0.4013 0.2906
MCF7 HG-5-113-01
3.33
uM
LJP5
 72
hr
 1389 1646 5905 0.2786 0.0840
MCF7 HG-5-113-01
10
uM
LJP5
 72
hr
 1389 990 5905 0.1674 -0.1512
MCF7 HG-5-88-01
0.04
uM
LJP6
 72
hr
 1389 3675 5445 0.6770 0.6408
MCF7 HG-5-88-01
0.12
uM
LJP6
 72
hr
 1389 3585 5445 0.6584 0.6171
MCF7 HG-5-88-01
0.37
uM
LJP6
 72
hr
 1389 3381 5445 0.6226 0.5710
MCF7 HG-5-88-01
1.11
uM
LJP6
 72
hr
 1389 2672 5445 0.4902 0.3914
MCF7 HG-5-88-01
3.33
uM
LJP6
 72
hr
 1389 1909 5445 0.3509 0.1747
MCF7 HG-5-88-01
10
uM
LJP6
 72
hr
 1389 1247 5445 0.2291 -0.0551
MCF7 HG-6-64-01
0.04
uM
LJP6
 72
hr
 1389 6450 5445 1.1889 1.1853
MCF7 HG-6-64-01
0.12
uM
LJP6
 72
hr
 1389 5981 5445 1.1007 1.1010
MCF7 HG-6-64-01
0.37
uM
LJP6
 72
hr
 1389 5714 5445 1.0532 1.0545
MCF7 HG-6-64-01
1.11
uM
LJP6
 72
hr
 1389 5483 5445 1.0109 1.0120
MCF7 HG-6-64-01
3.33
uM
LJP6
 72
hr
 1389 3449 5445 0.6335 0.5851
MCF7 HG-6-64-01
10
uM
LJP6
 72
hr
 1389 896 5445 0.1651 -0.1996
MCF7 Neratinib
0.04
uM
LJP5
 72
hr
 1389 3737 5905 0.6332 0.6068
MCF7 Neratinib
0.12
uM
LJP5
 72
hr
 1389 3990 5905 0.6742 0.6524
MCF7 Neratinib
0.37
uM
LJP5
 72
hr
 1389 3852 5905 0.6518 0.6287