LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Sorafenib
0.12
uM
LJP6
 72
hr
 1389 4987 5445 0.9147 0.9096
MCF7 Sorafenib
0.37
uM
LJP6
 72
hr
 1389 4946 5445 0.9088 0.9046
MCF7 Sorafenib
1.11
uM
LJP6
 72
hr
 1389 4660 5445 0.8537 0.8430
MCF7 Sorafenib
3.33
uM
LJP6
 72
hr
 1389 4391 5445 0.8027 0.7828
MCF7 Sorafenib
10
uM
LJP6
 72
hr
 1389 1891 5445 0.3485 0.1704
MCF7 CP466722
0.04
uM
LJP5
 72
hr
 1389 6297 5905 1.0662 1.0623
MCF7 CP466722
0.12
uM
LJP5
 72
hr
 1389 6357 5905 1.0767 1.0722
MCF7 CP466722
0.37
uM
LJP5
 72
hr
 1389 5956 5905 1.0082 1.0075
MCF7 CP466722
1.11
uM
LJP5
 72
hr
 1389 5956 5905 1.0090 1.0087
MCF7 CP466722
3.33
uM
LJP5
 72
hr
 1389 5916 5905 1.0023 1.0024
MCF7 CP466722
10
uM
LJP5
 72
hr
 1389 5776 5905 0.9766 0.9750
MCF7 CP724714
0.04
uM
LJP5
 72
hr
 1389 5239 5905 0.8877 0.8892
MCF7 CP724714
0.12
uM
LJP5
 72
hr
 1389 4654 5905 0.7877 0.7836
MCF7 CP724714
0.37
uM
LJP5
 72
hr
 1389 4622 5905 0.7829 0.7787
MCF7 CP724714
1.11
uM
LJP5
 72
hr
 1389 4672 5905 0.7922 0.7888
MCF7 CP724714
3.33
uM
LJP5
 72
hr
 1389 5059 5905 0.8573 0.8579
MCF7 CP724714
10
uM
LJP5
 72
hr
 1389 3532 5905 0.5978 0.5625
MCF7 Alvocidib
0.04
uM
LJP6
 72
hr
 1389 1631 5445 0.2990 0.0802
MCF7 Alvocidib
0.12
uM
LJP6
 72
hr
 1389 565 5445 0.1037 -0.3695
MCF7 Alvocidib
0.37
uM
LJP6
 72
hr
 1389 489 5445 0.0896 -0.4128
MCF7 Alvocidib
1.11
uM
LJP6
 72
hr
 1389 486 5445 0.0890 -0.4155
MCF7 Alvocidib
3.33
uM
LJP6
 72
hr
 1389 468 5445 0.0859 -0.4251
MCF7 Alvocidib
10
uM
LJP6
 72
hr
 1389 509 5445 0.0933 -0.4010
MCF7 GW843682X
0.04
uM
LJP6
 72
hr
 1389 4561 5445 0.8379 0.8267
MCF7 GW843682X
0.12
uM
LJP6
 72
hr
 1389 3078 5445 0.5636 0.4888