LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | NVP-TAE684 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1021 | 4056 | 0.2515 | -0.1058 |
| MCF7 | Crizotinib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1243 | 4267 | 0.2913 | 0.0030 |
| MCF7 | Dasatinib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 972 | 4267 | 0.2280 | -0.1257 |
| MCF7 | Imatinib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 4335 | 4056 | 1.0693 | 1.0789 |
| MCF7 | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 514 | 4056 | 0.1269 | -0.4009 |
| MCF7 | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 4840 | 4056 | 1.1932 | 1.2169 |
| MCF7 | HG-6-64-01 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 2586 | 4056 | 0.6377 | 0.5385 |
| MCF7 | JW-7-24-1 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1581 | 4056 | 0.3904 | 0.1550 |
| MCF7 | Dasatinib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 916 | 4056 | 0.2260 | -0.1601 |
| MCF7 | Tozasertib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1433 | 4267 | 0.3365 | 0.0872 |
| MCF7 | CGP60474 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 673 | 4267 | 0.1576 | -0.2896 |
| MCF7 | HG-5-113-01 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1371 | 4267 | 0.3216 | 0.0600 |
| MCF7 | CP466722 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 4230 | 4267 | 0.9910 | 0.9888 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 542 | 4056 | 0.1338 | -0.3813 |
| MCF7 | CP724714 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 3278 | 4267 | 0.7684 | 0.7259 |
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1057 | 4056 | 0.2607 | -0.0870 |
| MCF7 | HG-5-88-01 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1501 | 4056 | 0.3699 | 0.1198 |
| MCF7 | Neratinib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 2031 | 4267 | 0.4761 | 0.3201 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 3101 | 4267 | 0.7256 | 0.6698 |
| MCF7 | GW843682X | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1328 | 4056 | 0.3277 | 0.0433 |
| MCF7 | AT-7519 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 893 | 4056 | 0.2202 | -0.1723 |
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1242 | 4056 | 0.3066 | 0.0029 |
| MCF7 | Sorafenib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 3446 | 4056 | 0.8503 | 0.8195 |
| MCF7 | KIN001-043 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 3437 | 4056 | 0.8478 | 0.8164 |
| MCF7 | BMS345541 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 975 | 4056 | 0.2404 | -0.1289 |