LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Vemurafenib
0.04
uM
LJP5
 72
hr
 1235 4219 4267 0.9908 0.9890
MCF7 BMS345541
0.04
uM
LJP6
 72
hr
 1235 4482 4056 1.1046 1.1188
SK-BR-3 Palbociclib
0.04
uM
LJP6
 72
hr
 1476 3486 3643 0.9591 0.9400
SK-BR-3 QL-XII-47
0.04
uM
LJP6
 72
hr
 1476 2440 3643 0.6716 0.4737
SK-BR-3 Torin1
0.04
uM
LJP6
 72
hr
 1476 1523 3643 0.4188 0.0238
MCF7 PHA-665752
0.04
uM
LJP5
 72
hr
 1235 4485 4267 1.0528 1.0586
MCF7 Enzastaurin
0.04
uM
LJP5
 72
hr
 1235 4036 4267 0.9475 0.9410
MCF7 Dactolisib
0.04
uM
LJP5
 72
hr
 1235 1924 4267 0.4505 0.2798
MCF7 PI103
0.04
uM
LJP6
 72
hr
 1235 3469 4056 0.8555 0.8261
SK-BR-3 WZ3105
0.04
uM
LJP5
 72
hr
 1476 1114 3772 0.2953 -0.1883
MCF7 Gefitinib
0.04
uM
LJP6
 72
hr
 1235 4620 4056 1.1386 1.1569
MCF7 GSK 690693
0.04
uM
LJP5
 72
hr
 1235 2655 4267 0.6212 0.5305
MCF7 Palbociclib
0.04
uM
LJP6
 72
hr
 1235 3018 4056 0.7435 0.6816
MCF7 KIN001-043
0.04
uM
LJP6
 72
hr
 1235 3928 4056 0.9685 0.9632
MCF7 PD0325901
0.04
uM
LJP6
 72
hr
 1235 2945 4056 0.7255 0.6577
MCF7 Neratinib
0.04
uM
LJP5
 72
hr
 1235 3207 4267 0.7514 0.7040
MCF7 Mitoxantrone
0.04
uM
LJP5
 72
hr
 1235 1380 4267 0.3234 0.0624
SK-BR-3 PD0325901
0.04
uM
LJP5
 72
hr
 1476 3408 3772 0.9038 0.8561
MCF7 PF562271
0.04
uM
LJP6
 72
hr
 1235 3573 4056 0.8807 0.8566
MCF7 CP724714
0.04
uM
LJP5
 72
hr
 1235 3247 4267 0.7619 0.7178
MCF7 Radicicol
0.04
uM
LJP5
 72
hr
 1235 2719 4267 0.6374 0.5521
MCF7 SNS-032
0.04
uM
LJP6
 72
hr
 1235 726 4056 0.1789 -0.2671
SK-BR-3 YM 201636
0.04
uM
LJP5
 72
hr
 1476 4029 3772 1.0681 1.0994
MDA-MB-231 TWS119
0.04
uM
LJP5
 72
hr
 868 3371 3410 0.9878 0.9868
MDA-MB-231 YM 201636
0.04
uM
LJP5
 72
hr
 868 3606 3410 1.0563 1.0541