LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A A443654
1.11
uM
LJP6
 72
hr
 513 445 10473 0.0425 -0.0324
MCF 10A Withaferin A
1.11
uM
LJP5
 72
hr
 513 446 10362 0.0431 -0.0317
MCF 10A AZD8330
0.04
uM
LJP5
 72
hr
 513 447 10362 0.0431 -0.0330
MCF 10A Celastrol
3.33
uM
LJP6
 72
hr
 513 450 10473 0.0430 -0.0312
MCF 10A Alvocidib
0.37
uM
LJP6
 72
hr
 513 452 10473 0.0432 -0.0298
MDA-MB-231 Dasatinib
10
uM
LJP6
 72
hr
 868 456 3556 0.1281 -0.2730
MCF 10A Mitoxantrone
1.11
uM
LJP6
 72
hr
 513 458 10473 0.0438 -0.0267
MCF 10A GSK1059615
3.33
uM
LJP6
 72
hr
 513 459 10473 0.0438 -0.0260
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 72
hr
 868 460 3556 0.1292 -0.2691
MCF 10A Foretinib
10
uM
LJP5
 72
hr
 513 463 10362 0.0447 -0.0245
MCF 10A Mitoxantrone
10
uM
LJP6
 72
hr
 513 464 10473 0.0443 -0.0231
MCF 10A Luminespib
1.11
uM
LJP5
 72
hr
 513 465 10362 0.0449 -0.0229
Hs 578T Mitoxantrone
10
uM
LJP6
 72
hr
 929 466 3216 0.1450 -0.3206
MCF 10A Alvocidib
10
uM
LJP6
 72
hr
 513 467 10473 0.0447 -0.0214
MDA-MB-231 CGP60474
10
uM
LJP6
 72
hr
 868 469 3556 0.1316 -0.2652
MCF 10A Torin2
0.37
uM
LJP5
 72
hr
 513 472 10362 0.0455 -0.0205
MCF 10A Geldanamycin
1.11
uM
LJP6
 72
hr
 513 473 10473 0.0452 -0.0187
MCF 10A Luminespib
0.04
uM
LJP5
 72
hr
 513 474 10362 0.0457 -0.0185
MCF 10A Alvocidib
1.11
uM
LJP6
 72
hr
 513 476 10473 0.0455 -0.0173
MDA-MB-231 Withaferin A
10
uM
LJP5
 72
hr
 868 476 3410 0.1396 -0.2634
MCF 10A Luminespib
0.37
uM
LJP5
 72
hr
 513 476 10362 0.0459 -0.0176
MCF 10A AT-7519
10
uM
LJP6
 72
hr
 513 482 10473 0.0461 -0.0150
MCF 10A WZ-4-145
10
uM
LJP6
 72
hr
 513 483 10473 0.0461 -0.0145
MCF 10A CGP60474
3.33
uM
LJP6
 72
hr
 513 484 10473 0.0462 -0.0241
MCF 10A Torin2
1.11
uM
LJP5
 72
hr
 513 484 10362 0.0467 -0.0153