LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Nilotinib | 0.12 | uM | LJP5 | 72 | hr | 513 | 10609 | 10362 | 1.0239 | 1.0109 |
| MCF 10A | LDN-193189 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10621 | 10362 | 1.0251 | 1.0113 |
| MCF 10A | PLX-4720 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10627 | 10362 | 1.0254 | 1.0115 |
| MCF 10A | WH-4-025 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10673 | 10362 | 1.0305 | 1.0133 |
| MCF 10A | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 513 | 10692 | 10473 | 1.0210 | 1.0095 |
| MCF 10A | XL147 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10693 | 10362 | 1.0321 | 1.0145 |
| MCF 10A | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 513 | 10700 | 10362 | 1.0328 | 1.0148 |
| MCF 10A | TWS119 | 0.12 | uM | LJP5 | 72 | hr | 513 | 10711 | 10362 | 1.0337 | 1.0153 |
| MCF 10A | Imatinib | 0.04 | uM | LJP6 | 72 | hr | 513 | 10714 | 10473 | 1.0230 | 1.0105 |
| MCF 10A | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 513 | 10715 | 10362 | 1.0340 | 1.0153 |
| MCF 10A | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 513 | 10721 | 10362 | 1.0349 | 1.0157 |
| MCF 10A | CP466722 | 0.37 | uM | LJP5 | 72 | hr | 513 | 10725 | 10362 | 1.0350 | 1.0159 |
| MCF 10A | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10774 | 10362 | 1.0399 | 1.0179 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 513 | 10826 | 10473 | 1.0337 | 1.0152 |
| MCF 10A | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10835 | 10362 | 1.0457 | 1.0206 |
| MCF 10A | CP466722 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10852 | 10362 | 1.0473 | 1.0214 |
| MCF 10A | Nintedanib | 0.04 | uM | LJP6 | 72 | hr | 513 | 10876 | 10473 | 1.0384 | 1.0171 |
| MCF 10A | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 10885 | 10362 | 1.0506 | 1.0228 |
| MCF 10A | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10892 | 10362 | 1.0515 | 1.0230 |
| MCF 10A | Saracatinib | 0.04 | uM | LJP6 | 72 | hr | 513 | 10896 | 10473 | 1.0404 | 1.0182 |
| MCF 10A | TWS119 | 0.37 | uM | LJP5 | 72 | hr | 513 | 10898 | 10362 | 1.0517 | 1.0233 |
| MCF 10A | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 513 | 10904 | 10473 | 1.0413 | 1.0186 |
| MCF 10A | PD173074 | 0.04 | uM | LJP6 | 72 | hr | 513 | 10923 | 10473 | 1.0430 | 1.0194 |
| MCF 10A | Nilotinib | 0.04 | uM | LJP5 | 72 | hr | 513 | 10927 | 10362 | 1.0548 | 1.0246 |
| MCF 10A | CP466722 | 0.12 | uM | LJP5 | 72 | hr | 513 | 10964 | 10362 | 1.0581 | 1.0262 |