LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A WYE-125132
0.37
uM
LJP6
 72
hr
 513 1303 10473 0.1245 0.2383
BT-20 CGP60474
10
uM
LJP6
 72
hr
 1657 673 5383 0.1252 -0.4116
MCF 10A XMD16-144
3.33
uM
LJP5
 72
hr
 513 1297 10362 0.1253 0.2376
MCF 10A OSI-027
1.11
uM
LJP6
 72
hr
 513 1313 10473 0.1253 0.2390
MCF 10A XMD16-144
1.11
uM
LJP5
 72
hr
 513 1303 10362 0.1257 0.2389
MCF7 Alvocidib
10
uM
LJP6
 72
hr
 1235 512 4056 0.1258 -0.4073
MCF 10A Barasertib
10
uM
LJP5
 72
hr
 513 1307 10362 0.1261 0.2403
MCF 10A Barasertib
0.37
uM
LJP5
 72
hr
 513 1313 10362 0.1268 0.2419
MCF7 CGP60474
3.33
uM
LJP6
 72
hr
 1235 514 4056 0.1269 -0.4009
Hs 578T Withaferin A
10
uM
LJP6
 72
hr
 929 411 3216 0.1277 -0.3680
MCF 10A BX-912
3.33
uM
LJP5
 72
hr
 513 1326 10362 0.1280 0.2446
MDA-MB-231 Dasatinib
10
uM
LJP6
 72
hr
 868 456 3556 0.1281 -0.2730
MCF 10A Barasertib
0.12
uM
LJP5
 72
hr
 513 1333 10362 0.1287 0.2459
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 72
hr
 868 460 3556 0.1292 -0.2691
MCF 10A Buparlisib
1.11
uM
LJP5
 72
hr
 513 1357 10362 0.1309 0.2500
MDA-MB-231 CGP60474
10
uM
LJP6
 72
hr
 868 469 3556 0.1316 -0.2652
MCF 10A Barasertib
3.33
uM
LJP5
 72
hr
 513 1376 10362 0.1328 0.2553
MCF 10A Torin1
0.12
uM
LJP6
 72
hr
 513 1397 10473 0.1334 0.2583
MCF7 Alvocidib
3.33
uM
LJP6
 72
hr
 1235 542 4056 0.1338 -0.3813
MCF 10A Pictilisib
1.11
uM
LJP6
 72
hr
 513 1404 10473 0.1341 0.2602
MCF 10A YM 201636
10
uM
LJP5
 72
hr
 513 1389 10362 0.1341 0.2576
MCF7 LDN-193189
10
uM
LJP5
 72
hr
 1235 573 4267 0.1346 -0.3496
MCF7 CGP60474
1.11
uM
LJP6
 72
hr
 1235 551 4056 0.1358 -0.3756
MCF 10A Barasertib
0.04
uM
LJP5
 72
hr
 513 1407 10362 0.1358 0.2617
MCF7 Geldanamycin
10
uM
LJP6
 72
hr
 1235 552 4056 0.1361 -0.3753