LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Mitoxantrone
3.33
uM
LJP6
 72
hr
 868 645 3556 0.1813 -0.1364
Hs 578T Torin1
10
uM
LJP6
 72
hr
 929 1031 3216 0.3208 0.0592
MDA-MB-231 Mitoxantrone
10
uM
LJP6
 72
hr
 868 290 3556 0.0816 -0.4170
MCF 10A Afatinib
0.04
uM
LJP6
 72
hr
 513 351 10473 0.0335 -0.0847
MDA-MB-231 Radicicol
0.04
uM
LJP6
 72
hr
 868 3982 3556 1.1199 1.1137
MCF 10A CGP60474
0.04
uM
LJP6
 72
hr
 513 542 10473 0.0518 0.0081
MDA-MB-231 Radicicol
0.12
uM
LJP6
 72
hr
 868 2529 3556 0.7108 0.6902
MCF 10A PD0325901
0.04
uM
LJP6
 72
hr
 513 1025 10473 0.0979 0.1696
MDA-MB-231 Radicicol
0.37
uM
LJP6
 72
hr
 868 1679 3556 0.4724 0.3830
MCF 10A CGP60474
0.12
uM
LJP6
 72
hr
 513 550 10473 0.0526 0.0149
MDA-MB-231 Radicicol
1.11
uM
LJP6
 72
hr
 868 1277 3556 0.3591 0.2086
MCF 10A Afatinib
0.12
uM
LJP6
 72
hr
 513 427 10473 0.0408 -0.0420
MDA-MB-231 Radicicol
3.33
uM
LJP6
 72
hr
 868 1277 3556 0.3593 0.2090
MCF 10A CGP60474
0.37
uM
LJP6
 72
hr
 513 572 10473 0.0546 0.0192
MDA-MB-231 Radicicol
10
uM
LJP6
 72
hr
 868 1066 3556 0.2997 0.1058