LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 LDN-193189
10
uM
LJP5
 72
hr
 868 332 3410 0.0973 -0.3860
MDA-MB-231 Mitoxantrone
10
uM
LJP5
 72
hr
 868 331 3410 0.0969 -0.3874
MCF 10A Buparlisib
10
uM
LJP5
 72
hr
 513 331 10362 0.0320 -0.0963
MCF 10A Withaferin A
10
uM
LJP6
 72
hr
 513 325 10473 0.0310 -0.1050
MCF 10A Withaferin A
10
uM
LJP5
 72
hr
 513 321 10362 0.0310 -0.1046
MCF 10A GSK1059615
10
uM
LJP6
 72
hr
 513 317 10473 0.0302 -0.1063
MCF 10A Geldanamycin
10
uM
LJP5
 72
hr
 513 307 10362 0.0297 -0.1119
MCF 10A Dasatinib
3.33
uM
LJP6
 72
hr
 513 305 10473 0.0291 -0.1141
MDA-MB-231 Mitoxantrone
10
uM
LJP6
 72
hr
 868 290 3556 0.0816 -0.4170
MCF 10A GSK1059615
10
uM
LJP5
 72
hr
 513 283 10362 0.0273 -0.1286
MCF 10A Geldanamycin
10
uM
LJP6
 72
hr
 513 262 10473 0.0250 -0.1442
MCF 10A HG-6-64-01
10
uM
LJP6
 72
hr
 513 246 10473 0.0235 -0.1572
MCF 10A Canertinib
10
uM
LJP6
 72
hr
 513 223 10473 0.0213 -0.1849
MCF 10A Dasatinib
10
uM
LJP6
 72
hr
 513 217 10473 0.0207 -0.1805
MCF 10A LDN-193189
10
uM
LJP5
 72
hr
 513 132 10362 0.0128 -0.2695