LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Mitoxantrone
10
uM
LJP6
 72
hr
 868 290 3556 0.0816 -0.4170
SK-BR-3 CGP60474
10
uM
LJP6
 72
hr
 1476 732 3643 0.2016 -0.4177
BT-20 A443654
10
uM
LJP6
 72
hr
 1657 652 5383 0.1212 -0.4241
SK-BR-3 Geldanamycin
10
uM
LJP6
 72
hr
 1476 688 3643 0.1889 -0.4449
SK-BR-3 LDN-193189
10
uM
LJP5
 72
hr
 1476 662 3772 0.1758 -0.4476
MCF7 Mitoxantrone
10
uM
LJP5
 72
hr
 1235 420 4267 0.0987 -0.4544
MCF7 Canertinib
10
uM
LJP6
 72
hr
 1235 430 4056 0.1061 -0.4595
SK-BR-3 QL-XII-47
10
uM
LJP6
 72
hr
 1476 659 3643 0.1810 -0.4631
SK-BR-3 Mitoxantrone
10
uM
LJP5
 72
hr
 1476 630 3772 0.1671 -0.4674
BT-20 LDN-193189
10
uM
LJP5
 72
hr
 1657 545 5588 0.0977 -0.4702
MCF7 Mitoxantrone
10
uM
LJP6
 72
hr
 1235 408 4056 0.1006 -0.4766
SK-BR-3 Geldanamycin
10
uM
LJP5
 72
hr
 1476 597 3772 0.1583 -0.4897
MCF7 CGP60474
10
uM
LJP6
 72
hr
 1235 383 4056 0.0945 -0.4947
MCF7 AZD 5438
10
uM
LJP6
 72
hr
 1235 381 4056 0.0939 -0.4975
SK-BR-3 Mitoxantrone
10
uM
LJP6
 72
hr
 1476 544 3643 0.1497 -0.5368