LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A GSK1059615
0.04
uM
LJP5
 72
hr
 513 10000 10362 0.9651 0.9836
MCF 10A GSK1059615
0.04
uM
LJP6
 72
hr
 513 8625 10473 0.8236 0.9126
MCF 10A GSK1059615
0.12
uM
LJP5
 72
hr
 513 7518 10362 0.7254 0.8571
MCF 10A GSK1059615
0.12
uM
LJP6
 72
hr
 513 5019 10473 0.4788 0.6853
MCF 10A GSK1059615
0.37
uM
LJP5
 72
hr
 513 2539 10362 0.2449 0.4440
MCF 10A GSK1059615
0.37
uM
LJP6
 72
hr
 513 2001 10473 0.1911 0.3664
MCF 10A GSK1059615
1.11
uM
LJP5
 72
hr
 513 593 10362 0.0572 0.0334
MCF 10A GSK1059615
1.11
uM
LJP6
 72
hr
 513 778 10473 0.0743 0.0995
MCF 10A GSK1059615
3.33
uM
LJP5
 72
hr
 513 348 10362 0.0336 -0.0875
MCF 10A GSK1059615
3.33
uM
LJP6
 72
hr
 513 459 10473 0.0438 -0.0260
MCF 10A GSK1059615
10
uM
LJP5
 72
hr
 513 283 10362 0.0273 -0.1286
MCF 10A GSK1059615
10
uM
LJP6
 72
hr
 513 317 10473 0.0302 -0.1063
MCF 10A Brivanib
0.04
uM
LJP5
 72
hr
 513 9764 10362 0.9421 0.9726
MCF 10A Brivanib
0.12
uM
LJP5
 72
hr
 513 9366 10362 0.9037 0.9537
MCF 10A Brivanib
0.37
uM
LJP5
 72
hr
 513 9301 10362 0.8976 0.9508
MCF 10A Brivanib
1.11
uM
LJP5
 72
hr
 513 7272 10362 0.7015 0.8425
MCF 10A Brivanib
3.33
uM
LJP5
 72
hr
 513 4641 10362 0.4476 0.6600
MCF 10A Brivanib
10
uM
LJP5
 72
hr
 513 1479 10362 0.1428 0.2765
MCF 10A CHIR-99021
0.04
uM
LJP6
 72
hr
 513 9979 10473 0.9528 0.9776
MCF 10A CHIR-99021
0.12
uM
LJP6
 72
hr
 513 9570 10473 0.9138 0.9587
MCF 10A CHIR-99021
0.37
uM
LJP6
 72
hr
 513 8716 10473 0.8322 0.9173
MCF 10A CHIR-99021
1.11
uM
LJP6
 72
hr
 513 6771 10473 0.6464 0.8082
MCF 10A CHIR-99021
3.33
uM
LJP6
 72
hr
 513 6115 10473 0.5838 0.7670
MCF 10A CHIR-99021
10
uM
LJP6
 72
hr
 513 4632 10473 0.4423 0.6542
MCF 10A Linifanib
0.04
uM
LJP6
 72
hr
 513 11575 10473 1.1054 1.0465