LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A BX-912
1.11
uM
LJP5
 3
L21
 72
hr
 962 1751 10315 0.1698 0.1912
MCF 10A BX-912
3.33
uM
LJP5
 1
L20
 72
hr
 962 1603 10714 0.1496 0.1581
MCF 10A BX-912
3.33
uM
LJP5
 2
L20
 72
hr
 962 1542 10507 0.1468 0.1465
MCF 10A BX-912
3.33
uM
LJP5
 3
L20
 72
hr
 962 1684 10315 0.1633 0.1777
MCF 10A BX-912
10
uM
LJP5
 1
L19
 72
hr
 962 1148 10714 0.1072 0.0521
MCF 10A BX-912
10
uM
LJP5
 2
L19
 72
hr
 962 1198 10507 0.1140 0.0656
MCF 10A BX-912
10
uM
LJP5
 3
L19
 72
hr
 962 1140 10315 0.1105 0.0508
MCF 10A Selumetinib
0.04
uM
LJP6
 1
M12
 72
hr
 962 5135 10693 0.4802 0.6193
MCF 10A Selumetinib
0.04
uM
LJP6
 2
M12
 72
hr
 962 4991 10740 0.4647 0.6047
MCF 10A Selumetinib
0.04
uM
LJP6
 3
M12
 72
hr
 962 4807 10641 0.4517 0.5903
MCF 10A Selumetinib
0.12
uM
LJP6
 1
M11
 72
hr
 962 4180 10693 0.3909 0.5262
MCF 10A Selumetinib
0.12
uM
LJP6
 2
M11
 72
hr
 962 4021 10740 0.3744 0.5081
MCF 10A Selumetinib
0.12
uM
LJP6
 3
M11
 72
hr
 962 3613 10641 0.3395 0.4646
MCF 10A Selumetinib
0.37
uM
LJP6
 1
M10
 72
hr
 962 3407 10693 0.3186 0.4390
MCF 10A Selumetinib
0.37
uM
LJP6
 2
M10
 72
hr
 962 3474 10740 0.3234 0.4461
MCF 10A Selumetinib
0.37
uM
LJP6
 3
M10
 72
hr
 962 2822 10641 0.2652 0.3639
MCF 10A Selumetinib
1.11
uM
LJP6
 1
M09
 72
hr
 962 2649 10693 0.2477 0.3384
MCF 10A Selumetinib
1.11
uM
LJP6
 2
M09
 72
hr
 962 2642 10740 0.2460 0.3367
MCF 10A Selumetinib
1.11
uM
LJP6
 3
M09
 72
hr
 962 2343 10641 0.2202 0.2926
MCF 10A Selumetinib
3.33
uM
LJP6
 1
M08
 72
hr
 962 2197 10693 0.2055 0.2683
MCF 10A Selumetinib
3.33
uM
LJP6
 2
M08
 72
hr
 962 2379 10740 0.2215 0.2970
MCF 10A Selumetinib
3.33
uM
LJP6
 3
M08
 72
hr
 962 2103 10641 0.1976 0.2530
MCF 10A Selumetinib
10
uM
LJP6
 1
M07
 72
hr
 962 1721 10693 0.1609 0.1822
MCF 10A Selumetinib
10
uM
LJP6
 2
M07
 72
hr
 962 1826 10740 0.1700 0.2021
MCF 10A Selumetinib
10
uM
LJP6
 3
M07
 72
hr
 962 1531 10641 0.1439 0.1434