LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A KIN001-043
3.33
uM
LJP6
 2
C08
 72
hr
 962 8427 10740 0.7846 0.8653
MCF 10A KIN001-043
3.33
uM
LJP6
 3
C08
 72
hr
 962 9090 10641 0.8542 0.9111
MCF 10A KIN001-043
10
uM
LJP6
 1
C07
 72
hr
 962 4672 10693 0.4369 0.5759
MCF 10A KIN001-043
10
uM
LJP6
 2
C07
 72
hr
 962 4535 10740 0.4222 0.5612
MCF 10A KIN001-043
10
uM
LJP6
 3
C07
 72
hr
 962 5638 10641 0.5298 0.6652
MCF 10A Saracatinib
0.04
uM
LJP6
 1
D12
 72
hr
 962 10687 10693 0.9994 0.9996
MCF 10A Saracatinib
0.04
uM
LJP6
 2
D12
 72
hr
 962 10602 10740 0.9871 0.9925
MCF 10A Saracatinib
0.04
uM
LJP6
 3
D12
 72
hr
 962 11033 10641 1.0368 1.0209
MCF 10A Saracatinib
0.12
uM
LJP6
 1
D11
 72
hr
 962 9965 10693 0.9319 0.9598
MCF 10A Saracatinib
0.12
uM
LJP6
 2
D11
 72
hr
 962 9899 10740 0.9216 0.9537
MCF 10A Saracatinib
0.12
uM
LJP6
 3
D11
 72
hr
 962 10928 10641 1.0269 1.0154
MCF 10A Saracatinib
0.37
uM
LJP6
 1
D10
 72
hr
 962 9533 10693 0.8915 0.9350
MCF 10A Saracatinib
0.37
uM
LJP6
 2
D10
 72
hr
 962 9276 10740 0.8636 0.9175
MCF 10A Saracatinib
0.37
uM
LJP6
 3
D10
 72
hr
 962 10227 10641 0.9610 0.9772
MCF 10A Saracatinib
1.11
uM
LJP6
 1
D09
 72
hr
 962 8092 10693 0.7567 0.8458
MCF 10A Saracatinib
1.11
uM
LJP6
 2
D09
 72
hr
 962 7904 10740 0.7359 0.8313
MCF 10A Saracatinib
1.11
uM
LJP6
 3
D09
 72
hr
 962 8653 10641 0.8131 0.8842
MCF 10A Saracatinib
3.33
uM
LJP6
 1
D08
 72
hr
 962 5225 10693 0.4886 0.6274
MCF 10A Saracatinib
3.33
uM
LJP6
 2
D08
 72
hr
 962 4852 10740 0.4517 0.5918
MCF 10A Saracatinib
3.33
uM
LJP6
 3
D08
 72
hr
 962 6250 10641 0.5873 0.7154
MCF 10A Saracatinib
10
uM
LJP6
 1
D07
 72
hr
 962 1382 10693 0.1292 0.1099
MCF 10A Saracatinib
10
uM
LJP6
 2
D07
 72
hr
 962 1286 10740 0.1197 0.0869
MCF 10A Saracatinib
10
uM
LJP6
 3
D07
 72
hr
 962 1363 10641 0.1281 0.1057
MCF 10A Sigma A6730
0.04
uM
LJP5
 1
B24
 72
hr
 962 10370 10714 0.9679 0.9813
MCF 10A Sigma A6730
0.04
uM
LJP5
 2
B24
 72
hr
 962 10789 10507 1.0268 1.0154