LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A MK2206
0.04
uM
LJP6
 1
F06
 72
hr
 962 9650 10693 0.9024 0.9418
MCF 10A MK2206
0.04
uM
LJP6
 2
F06
 72
hr
 962 9739 10740 0.9067 0.9445
MCF 10A MK2206
0.04
uM
LJP6
 3
F06
 72
hr
 962 9876 10641 0.9281 0.9574
MCF 10A MK2206
0.12
uM
LJP6
 1
F05
 72
hr
 962 9734 10693 0.9103 0.9466
MCF 10A MK2206
0.12
uM
LJP6
 2
F05
 72
hr
 962 9625 10740 0.8961 0.9380
MCF 10A MK2206
0.12
uM
LJP6
 3
F05
 72
hr
 962 9324 10641 0.8762 0.9252
MCF 10A MK2206
0.37
uM
LJP6
 1
F04
 72
hr
 962 9124 10693 0.8532 0.9107
MCF 10A MK2206
0.37
uM
LJP6
 2
F04
 72
hr
 962 9900 10740 0.9217 0.9537
MCF 10A MK2206
0.37
uM
LJP6
 3
F04
 72
hr
 962 8840 10641 0.8307 0.8958
MCF 10A MK2206
1.11
uM
LJP6
 1
F03
 72
hr
 962 8662 10693 0.8100 0.8823
MCF 10A MK2206
1.11
uM
LJP6
 2
F03
 72
hr
 962 8218 10740 0.7651 0.8519
MCF 10A MK2206
1.11
uM
LJP6
 3
F03
 72
hr
 962 8443 10641 0.7934 0.8709
MCF 10A MK2206
3.33
uM
LJP6
 1
F02
 72
hr
 962 7878 10693 0.7367 0.8316
MCF 10A MK2206
3.33
uM
LJP6
 2
F02
 72
hr
 962 7586 10740 0.7063 0.8098
MCF 10A MK2206
3.33
uM
LJP6
 3
F02
 72
hr
 962 7659 10641 0.7197 0.8190
MCF 10A MK2206
10
uM
LJP6
 1
F01
 72
hr
 962 2911 10693 0.2722 0.3753
MCF 10A MK2206
10
uM
LJP6
 2
F01
 72
hr
 962 3043 10740 0.2833 0.3921
MCF 10A MK2206
10
uM
LJP6
 3
F01
 72
hr
 962 2820 10641 0.2650 0.3636
MCF 10A AZD-6482
0.04
uM
LJP5
 1
I06
 72
hr
 962 10728 10714 1.0013 1.0008
MCF 10A AZD-6482
0.04
uM
LJP5
 2
I06
 72
hr
 962 10744 10507 1.0225 1.0129
MCF 10A AZD-6482
0.04
uM
LJP5
 3
I06
 72
hr
 962 10176 10315 0.9865 0.9921
MCF 10A AZD-6482
0.12
uM
LJP5
 1
I05
 72
hr
 962 10325 10714 0.9637 0.9788
MCF 10A AZD-6482
0.12
uM
LJP5
 2
I05
 72
hr
 962 10640 10507 1.0126 1.0073
MCF 10A AZD-6482
0.12
uM
LJP5
 3
I05
 72
hr
 962 10046 10315 0.9739 0.9846
MCF 10A AZD-6482
0.37
uM
LJP5
 1
I04
 72
hr
 962 10131 10714 0.9456 0.9681