LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 GSK1059615
1.11
uM
LJP5
 3
E03
 72
hr
 1235 2824 4929 0.5729 0.5129
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 1
C02
 72
hr
 1235 1175 4355 0.2698 -0.0274
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 2
C02
 72
hr
 1235 576 4277 0.1347 -0.3471
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 3
C02
 72
hr
 1235 1813 4583 0.3956 0.2246
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 1
E02
 72
hr
 1235 1177 4474 0.2630 -0.0260
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 2
E02
 72
hr
 1235 984 4578 0.2149 -0.1137
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 3
E02
 72
hr
 1235 1193 4929 0.2420 -0.0176
MDA-MB-231 GSK1059615
10
uM
LJP6
 1
C01
 72
hr
 1235 837 4355 0.1922 -0.1930
MDA-MB-231 GSK1059615
10
uM
LJP6
 2
C01
 72
hr
 1235 437 4277 0.1022 -0.4404
MDA-MB-231 GSK1059615
10
uM
LJP6
 3
C01
 72
hr
 1235 1265 4583 0.2760 0.0124
MDA-MB-231 GSK1059615
10
uM
LJP5
 1
E01
 72
hr
 1235 503 4474 0.1124 -0.3839
MDA-MB-231 GSK1059615
10
uM
LJP5
 2
E01
 72
hr
 1235 381 4578 0.0832 -0.4636
MDA-MB-231 GSK1059615
10
uM
LJP5
 3
E01
 72
hr
 1235 670 4929 0.1359 -0.2642
MDA-MB-231 Brivanib
0.04
uM
LJP5
 1
P18
 72
hr
 1235 3629 4474 0.8110 0.7866
MDA-MB-231 Brivanib
0.04
uM
LJP5
 2
P18
 72
hr
 1235 4014 4578 0.8767 0.8654
MDA-MB-231 Brivanib
0.04
uM
LJP5
 3
P18
 72
hr
 1235 4558 4929 0.9247 0.9230
MDA-MB-231 Brivanib
0.12
uM
LJP5
 1
P17
 72
hr
 1235 4055 4474 0.9062 0.8966
MDA-MB-231 Brivanib
0.12
uM
LJP5
 2
P17
 72
hr
 1235 3900 4578 0.8518 0.8372
MDA-MB-231 Brivanib
0.12
uM
LJP5
 3
P17
 72
hr
 1235 4634 4929 0.9401 0.9390
MDA-MB-231 Brivanib
0.37
uM
LJP5
 1
P16
 72
hr
 1235 3863 4474 0.8633 0.8477
MDA-MB-231 Brivanib
0.37
uM
LJP5
 2
P16
 72
hr
 1235 3903 4578 0.8525 0.8380
MDA-MB-231 Brivanib
0.37
uM
LJP5
 3
P16
 72
hr
 1235 4795 4929 0.9728 0.9725
MDA-MB-231 Brivanib
1.11
uM
LJP5
 1
P15
 72
hr
 1235 3688 4474 0.8242 0.8021
MDA-MB-231 Brivanib
1.11
uM
LJP5
 2
P15
 72
hr
 1235 4228 4578 0.9234 0.9174
MDA-MB-231 Brivanib
1.11
uM
LJP5
 3
P15
 72
hr
 1235 4895 4929 0.9930 0.9930