LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 TGX221
10
uM
LJP5
 2
H19
 72
hr
 1235 3974 4578 0.8680 0.8556
MDA-MB-231 TGX221
10
uM
LJP5
 3
H19
 72
hr
 1235 4403 4929 0.8932 0.8900
MDA-MB-231 GSK1059615
0.04
uM
LJP6
 1
C06
 72
hr
 1235 4218 4355 0.9683 0.9649
MDA-MB-231 GSK1059615
0.04
uM
LJP6
 2
C06
 72
hr
 1235 3219 4277 0.7526 0.7065
MDA-MB-231 GSK1059615
0.04
uM
LJP6
 3
C06
 72
hr
 1235 4494 4583 0.9805 0.9793
MDA-MB-231 GSK1059615
0.04
uM
LJP5
 1
E06
 72
hr
 1235 4584 4474 1.0244 1.0262
MDA-MB-231 GSK1059615
0.04
uM
LJP5
 2
E06
 72
hr
 1235 4606 4578 1.0060 1.0063
MDA-MB-231 GSK1059615
0.04
uM
LJP5
 3
E06
 72
hr
 1235 5108 4929 1.0363 1.0360
MDA-MB-231 GSK1059615
0.12
uM
LJP6
 1
C05
 72
hr
 1235 4231 4355 0.9713 0.9682
MDA-MB-231 GSK1059615
0.12
uM
LJP6
 2
C05
 72
hr
 1235 3749 4277 0.8765 0.8581
MDA-MB-231 GSK1059615
0.12
uM
LJP6
 3
C05
 72
hr
 1235 4398 4583 0.9596 0.9568
MDA-MB-231 GSK1059615
0.12
uM
LJP5
 1
E05
 72
hr
 1235 4409 4474 0.9853 0.9841
MDA-MB-231 GSK1059615
0.12
uM
LJP5
 2
E05
 72
hr
 1235 4700 4578 1.0265 1.0279
MDA-MB-231 GSK1059615
0.12
uM
LJP5
 3
E05
 72
hr
 1235 4474 4929 0.9076 0.9052
MDA-MB-231 GSK1059615
0.37
uM
LJP6
 1
C04
 72
hr
 1235 4208 4355 0.9660 0.9623
MDA-MB-231 GSK1059615
0.37
uM
LJP6
 2
C04
 72
hr
 1235 3421 4277 0.7998 0.7655
MDA-MB-231 GSK1059615
0.37
uM
LJP6
 3
C04
 72
hr
 1235 4172 4583 0.9103 0.9030
MDA-MB-231 GSK1059615
0.37
uM
LJP5
 1
E04
 72
hr
 1235 3800 4474 0.8492 0.8314
MDA-MB-231 GSK1059615
0.37
uM
LJP5
 2
E04
 72
hr
 1235 4107 4578 0.8970 0.8882
MDA-MB-231 GSK1059615
0.37
uM
LJP5
 3
E04
 72
hr
 1235 4431 4929 0.8989 0.8960
MDA-MB-231 GSK1059615
1.11
uM
LJP6
 1
C03
 72
hr
 1235 2267 4355 0.5204 0.3963
MDA-MB-231 GSK1059615
1.11
uM
LJP6
 2
C03
 72
hr
 1235 1128 4277 0.2637 -0.0497
MDA-MB-231 GSK1059615
1.11
uM
LJP6
 3
C03
 72
hr
 1235 2978 4583 0.6497 0.5922
MDA-MB-231 GSK1059615
1.11
uM
LJP5
 1
E03
 72
hr
 1235 2409 4474 0.5384 0.4327
MDA-MB-231 GSK1059615
1.11
uM
LJP5
 2
E03
 72
hr
 1235 2124 4578 0.4639 0.3319