LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Linsitinib
1.11
uM
LJP5
 3
O21
 72
hr
 1235 4201 4929 0.8523 0.8460
MDA-MB-231 Linsitinib
3.33
uM
LJP5
 1
O20
 72
hr
 1235 3632 4474 0.8117 0.7874
MDA-MB-231 Linsitinib
3.33
uM
LJP5
 2
O20
 72
hr
 1235 3503 4578 0.7651 0.7357
MDA-MB-231 Linsitinib
3.33
uM
LJP5
 3
O20
 72
hr
 1235 4252 4929 0.8626 0.8572
MDA-MB-231 Linsitinib
10
uM
LJP5
 1
O19
 72
hr
 1235 3254 4474 0.7272 0.6846
MDA-MB-231 Linsitinib
10
uM
LJP5
 2
O19
 72
hr
 1235 3153 4578 0.6886 0.6417
MDA-MB-231 Linsitinib
10
uM
LJP5
 3
O19
 72
hr
 1235 3663 4929 0.7431 0.7235
MDA-MB-231 Ruxolitinib
0.04
uM
LJP5
 1
O18
 72
hr
 1235 3932 4474 0.8787 0.8654
MDA-MB-231 Ruxolitinib
0.04
uM
LJP5
 2
O18
 72
hr
 1235 4020 4578 0.8780 0.8669
MDA-MB-231 Ruxolitinib
0.04
uM
LJP5
 3
O18
 72
hr
 1235 4517 4929 0.9164 0.9144
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
 1
O17
 72
hr
 1235 3796 4474 0.8483 0.8304
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
 2
O17
 72
hr
 1235 3965 4578 0.8660 0.8533
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
 3
O17
 72
hr
 1235 4812 4929 0.9762 0.9760
MDA-MB-231 Ruxolitinib
0.37
uM
LJP5
 1
O16
 72
hr
 1235 3737 4474 0.8351 0.8150
MDA-MB-231 Ruxolitinib
0.37
uM
LJP5
 2
O16
 72
hr
 1235 3709 4578 0.8101 0.7890
MDA-MB-231 Ruxolitinib
0.37
uM
LJP5
 3
O16
 72
hr
 1235 4842 4929 0.9823 0.9822
MDA-MB-231 Ruxolitinib
1.11
uM
LJP5
 1
O15
 72
hr
 1235 3792 4474 0.8474 0.8294
MDA-MB-231 Ruxolitinib
1.11
uM
LJP5
 2
O15
 72
hr
 1235 4052 4578 0.8850 0.8748
MDA-MB-231 Ruxolitinib
1.11
uM
LJP5
 3
O15
 72
hr
 1235 4515 4929 0.9160 0.9139
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
 1
O14
 72
hr
 1235 3970 4474 0.8872 0.8751
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
 2
O14
 72
hr
 1235 4037 4578 0.8817 0.8711
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
 3
O14
 72
hr
 1235 4719 4929 0.9573 0.9568
MDA-MB-231 Ruxolitinib
10
uM
LJP5
 1
O13
 72
hr
 1235 2255 4474 0.5039 0.3826
MDA-MB-231 Ruxolitinib
10
uM
LJP5
 2
O13
 72
hr
 1235 2029 4578 0.4432 0.3000
MDA-MB-231 Ruxolitinib
10
uM
LJP5
 3
O13
 72
hr
 1235 2517 4929 0.5106 0.4281