LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PF477736
3.33
uM
LJP5
 2
J20
 72
hr
 1235 1456 4578 0.3180 0.0906
MDA-MB-231 PF477736
3.33
uM
LJP5
 3
J20
 72
hr
 1235 1625 4929 0.3297 0.1470
MDA-MB-231 PF477736
10
uM
LJP5
 1
J19
 72
hr
 1235 886 4474 0.1980 -0.1642
MDA-MB-231 PF477736
10
uM
LJP5
 2
J19
 72
hr
 1235 858 4578 0.1874 -0.1757
MDA-MB-231 PF477736
10
uM
LJP5
 3
J19
 72
hr
 1235 921 4929 0.1868 -0.1370
MDA-MB-231 LDN-193189
0.04
uM
LJP5
 1
G06
 72
hr
 1235 4302 4474 0.9614 0.9580
MDA-MB-231 LDN-193189
0.04
uM
LJP5
 2
G06
 72
hr
 1235 4318 4578 0.9431 0.9389
MDA-MB-231 LDN-193189
0.04
uM
LJP5
 3
G06
 72
hr
 1235 4716 4929 0.9567 0.9562
MDA-MB-231 LDN-193189
0.12
uM
LJP5
 1
G05
 72
hr
 1235 3928 4474 0.8778 0.8644
MDA-MB-231 LDN-193189
0.12
uM
LJP5
 2
G05
 72
hr
 1235 4216 4578 0.9208 0.9145
MDA-MB-231 LDN-193189
0.12
uM
LJP5
 3
G05
 72
hr
 1235 4320 4929 0.8764 0.8721
MDA-MB-231 LDN-193189
0.37
uM
LJP5
 1
G04
 72
hr
 1235 3861 4474 0.8629 0.8472
MDA-MB-231 LDN-193189
0.37
uM
LJP5
 2
G04
 72
hr
 1235 3830 4578 0.8365 0.8197
MDA-MB-231 LDN-193189
0.37
uM
LJP5
 3
G04
 72
hr
 1235 4574 4929 0.9279 0.9264
MDA-MB-231 LDN-193189
1.11
uM
LJP5
 1
G03
 72
hr
 1235 3356 4474 0.7500 0.7128
MDA-MB-231 LDN-193189
1.11
uM
LJP5
 2
G03
 72
hr
 1235 3375 4578 0.7371 0.7019
MDA-MB-231 LDN-193189
1.11
uM
LJP5
 3
G03
 72
hr
 1235 3173 4929 0.6437 0.6039
MDA-MB-231 LDN-193189
3.33
uM
LJP5
 1
G02
 72
hr
 1235 423 4474 0.0945 -0.4388
MDA-MB-231 LDN-193189
3.33
uM
LJP5
 2
G02
 72
hr
 1235 288 4578 0.0629 -0.5375
MDA-MB-231 LDN-193189
3.33
uM
LJP5
 3
G02
 72
hr
 1235 360 4929 0.0730 -0.4610
MDA-MB-231 LDN-193189
10
uM
LJP5
 1
G01
 72
hr
 1235 476 4474 0.1064 -0.4019
MDA-MB-231 LDN-193189
10
uM
LJP5
 2
G01
 72
hr
 1235 468 4578 0.1022 -0.4019
MDA-MB-231 LDN-193189
10
uM
LJP5
 3
G01
 72
hr
 1235 622 4929 0.1262 -0.2911
MDA-MB-231 PF431396
0.04
uM
LJP5
 1
E12
 72
hr
 1235 3959 4474 0.8848 0.8723
MDA-MB-231 PF431396
0.04
uM
LJP5
 2
E12
 72
hr
 1235 4274 4578 0.9335 0.9284