LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 3 | G09 | 72 | hr | 1209 | 1462 | 4121 | 0.3548 | 0.1131 |
| MCF7 | Celastrol | 3.33 | uM | LJP6 | 1 | G08 | 72 | hr | 1209 | 1147 | 3823 | 0.3000 | -0.0315 |
| MCF7 | Celastrol | 3.33 | uM | LJP6 | 2 | G08 | 72 | hr | 1209 | 997 | 4093 | 0.2435 | -0.1041 |
| MCF7 | Celastrol | 3.33 | uM | LJP6 | 3 | G08 | 72 | hr | 1209 | 883 | 4121 | 0.2143 | -0.1630 |
| MCF7 | Celastrol | 10 | uM | LJP6 | 1 | G07 | 72 | hr | 1209 | 541 | 3823 | 0.1415 | -0.3841 |
| MCF7 | Celastrol | 10 | uM | LJP6 | 2 | G07 | 72 | hr | 1209 | 485 | 4093 | 0.1185 | -0.4052 |
| MCF7 | Celastrol | 10 | uM | LJP6 | 3 | G07 | 72 | hr | 1209 | 550 | 4121 | 0.1335 | -0.3596 |
| MCF7 | SU11274 | 0.04 | uM | LJP5 | 1 | J12 | 72 | hr | 1209 | 4346 | 3980 | 1.0919 | 1.1050 |
| MCF7 | SU11274 | 0.04 | uM | LJP5 | 2 | J12 | 72 | hr | 1209 | 4155 | 4252 | 0.9770 | 0.9745 |
| MCF7 | SU11274 | 0.04 | uM | LJP5 | 3 | J12 | 72 | hr | 1209 | 4955 | 4376 | 1.1323 | 1.1385 |
| MCF7 | SU11274 | 0.12 | uM | LJP5 | 1 | J11 | 72 | hr | 1209 | 3679 | 3980 | 0.9244 | 0.9105 |
| MCF7 | SU11274 | 0.12 | uM | LJP5 | 2 | J11 | 72 | hr | 1209 | 4386 | 4252 | 1.0313 | 1.0343 |
| MCF7 | SU11274 | 0.12 | uM | LJP5 | 3 | J11 | 72 | hr | 1209 | 4541 | 4376 | 1.0377 | 1.0403 |
| MCF7 | SU11274 | 0.37 | uM | LJP5 | 1 | J10 | 72 | hr | 1209 | 3872 | 3980 | 0.9729 | 0.9682 |
| MCF7 | SU11274 | 0.37 | uM | LJP5 | 2 | J10 | 72 | hr | 1209 | 4148 | 4252 | 0.9754 | 0.9727 |
| MCF7 | SU11274 | 0.37 | uM | LJP5 | 3 | J10 | 72 | hr | 1209 | 3903 | 4376 | 0.8919 | 0.8804 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 1 | J09 | 72 | hr | 1209 | 3565 | 3980 | 0.8957 | 0.8758 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 2 | J09 | 72 | hr | 1209 | 3692 | 4252 | 0.8681 | 0.8500 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 3 | J09 | 72 | hr | 1209 | 3571 | 4376 | 0.8160 | 0.7924 |
| MCF7 | SU11274 | 3.33 | uM | LJP5 | 1 | J08 | 72 | hr | 1209 | 2886 | 3980 | 0.7251 | 0.6588 |
| MCF7 | SU11274 | 3.33 | uM | LJP5 | 2 | J08 | 72 | hr | 1209 | 3255 | 4252 | 0.7654 | 0.7259 |
| MCF7 | SU11274 | 3.33 | uM | LJP5 | 3 | J08 | 72 | hr | 1209 | 3184 | 4376 | 0.7276 | 0.6849 |
| MCF7 | SU11274 | 10 | uM | LJP5 | 1 | J07 | 72 | hr | 1209 | 1330 | 3980 | 0.3342 | 0.0568 |
| MCF7 | SU11274 | 10 | uM | LJP5 | 2 | J07 | 72 | hr | 1209 | 1400 | 4252 | 0.3292 | 0.0839 |
| MCF7 | SU11274 | 10 | uM | LJP5 | 3 | J07 | 72 | hr | 1209 | 1256 | 4376 | 0.2870 | 0.0205 |