LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | XMD16-144 | 3.33 | uM | LJP5 | 2 | M08 | 72 | hr | 1209 | 1427 | 4252 | 0.3355 | 0.0954 |
| MCF7 | XMD16-144 | 3.33 | uM | LJP5 | 3 | M08 | 72 | hr | 1209 | 1425 | 4376 | 0.3256 | 0.0924 |
| MCF7 | XMD16-144 | 10 | uM | LJP5 | 1 | M07 | 72 | hr | 1209 | 689 | 3980 | 0.1731 | -0.2793 |
| MCF7 | XMD16-144 | 10 | uM | LJP5 | 2 | M07 | 72 | hr | 1209 | 666 | 4252 | 0.1566 | -0.2803 |
| MCF7 | XMD16-144 | 10 | uM | LJP5 | 3 | M07 | 72 | hr | 1209 | 702 | 4376 | 0.1604 | -0.2542 |
| MCF7 | Erlotinib | 0.04 | uM | LJP5 | 1 | M24 | 72 | hr | 1209 | 3889 | 3980 | 0.9771 | 0.9732 |
| MCF7 | Erlotinib | 0.04 | uM | LJP5 | 2 | M24 | 72 | hr | 1209 | 3815 | 4252 | 0.8971 | 0.8837 |
| MCF7 | Erlotinib | 0.04 | uM | LJP5 | 3 | M24 | 72 | hr | 1209 | 3920 | 4376 | 0.8958 | 0.8848 |
| MCF7 | Erlotinib | 0.12 | uM | LJP5 | 1 | M23 | 72 | hr | 1209 | 3684 | 3980 | 0.9256 | 0.9120 |
| MCF7 | Erlotinib | 0.12 | uM | LJP5 | 2 | M23 | 72 | hr | 1209 | 3747 | 4252 | 0.8811 | 0.8652 |
| MCF7 | Erlotinib | 0.12 | uM | LJP5 | 3 | M23 | 72 | hr | 1209 | 4158 | 4376 | 0.9502 | 0.9456 |
| MCF7 | Erlotinib | 0.37 | uM | LJP5 | 1 | M22 | 72 | hr | 1209 | 4076 | 3980 | 1.0241 | 1.0279 |
| MCF7 | Erlotinib | 0.37 | uM | LJP5 | 2 | M22 | 72 | hr | 1209 | 4153 | 4252 | 0.9765 | 0.9740 |
| MCF7 | Erlotinib | 0.37 | uM | LJP5 | 3 | M22 | 72 | hr | 1209 | 4396 | 4376 | 1.0045 | 1.0049 |
| MCF7 | Erlotinib | 1.11 | uM | LJP5 | 1 | M21 | 72 | hr | 1209 | 4115 | 3980 | 1.0339 | 1.0392 |
| MCF7 | Erlotinib | 1.11 | uM | LJP5 | 2 | M21 | 72 | hr | 1209 | 4383 | 4252 | 1.0306 | 1.0335 |
| MCF7 | Erlotinib | 1.11 | uM | LJP5 | 3 | M21 | 72 | hr | 1209 | 4428 | 4376 | 1.0118 | 1.0127 |
| MCF7 | Erlotinib | 3.33 | uM | LJP5 | 1 | M20 | 72 | hr | 1209 | 4230 | 3980 | 1.0628 | 1.0722 |
| MCF7 | Erlotinib | 3.33 | uM | LJP5 | 2 | M20 | 72 | hr | 1209 | 4366 | 4252 | 1.0266 | 1.0292 |
| MCF7 | Erlotinib | 3.33 | uM | LJP5 | 3 | M20 | 72 | hr | 1209 | 4157 | 4376 | 0.9499 | 0.9454 |
| MCF7 | Erlotinib | 10 | uM | LJP5 | 1 | M19 | 72 | hr | 1209 | 3647 | 3980 | 0.9163 | 0.9008 |
| MCF7 | Erlotinib | 10 | uM | LJP5 | 2 | M19 | 72 | hr | 1209 | 3898 | 4252 | 0.9166 | 0.9062 |
| MCF7 | Erlotinib | 10 | uM | LJP5 | 3 | M19 | 72 | hr | 1209 | 3408 | 4376 | 0.7788 | 0.7478 |
| MCF7 | Gefitinib | 0.04 | uM | LJP6 | 1 | N12 | 72 | hr | 1209 | 3989 | 3823 | 1.0434 | 1.0519 |
| MCF7 | Gefitinib | 0.04 | uM | LJP6 | 2 | N12 | 72 | hr | 1209 | 4298 | 4093 | 1.0499 | 1.0561 |