LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PF431396 | 0.12 | uM | LJP5 | 2 | E11 | 72 | hr | 1209 | 2181 | 4252 | 0.5128 | 0.3840 |
| MCF7 | PF431396 | 0.12 | uM | LJP5 | 3 | E11 | 72 | hr | 1209 | 2480 | 4376 | 0.5667 | 0.4726 |
| MCF7 | PF431396 | 0.37 | uM | LJP5 | 1 | E10 | 72 | hr | 1209 | 1544 | 3980 | 0.3879 | 0.1527 |
| MCF7 | PF431396 | 0.37 | uM | LJP5 | 2 | E10 | 72 | hr | 1209 | 1461 | 4252 | 0.3435 | 0.1097 |
| MCF7 | PF431396 | 0.37 | uM | LJP5 | 3 | E10 | 72 | hr | 1209 | 1406 | 4376 | 0.3213 | 0.0845 |
| MCF7 | PF431396 | 1.11 | uM | LJP5 | 1 | E09 | 72 | hr | 1209 | 1342 | 3980 | 0.3372 | 0.0623 |
| MCF7 | PF431396 | 1.11 | uM | LJP5 | 2 | E09 | 72 | hr | 1209 | 1222 | 4252 | 0.2873 | 0.0057 |
| MCF7 | PF431396 | 1.11 | uM | LJP5 | 3 | E09 | 72 | hr | 1209 | 1304 | 4376 | 0.2980 | 0.0414 |
| MCF7 | PF431396 | 3.33 | uM | LJP5 | 1 | E08 | 72 | hr | 1209 | 1184 | 3980 | 0.2975 | -0.0124 |
| MCF7 | PF431396 | 3.33 | uM | LJP5 | 2 | E08 | 72 | hr | 1209 | 997 | 4252 | 0.2344 | -0.1011 |
| MCF7 | PF431396 | 3.33 | uM | LJP5 | 3 | E08 | 72 | hr | 1209 | 1026 | 4376 | 0.2345 | -0.0849 |
| MCF7 | PF431396 | 10 | uM | LJP5 | 1 | E07 | 72 | hr | 1209 | 671 | 3980 | 0.1686 | -0.2903 |
| MCF7 | PF431396 | 10 | uM | LJP5 | 2 | E07 | 72 | hr | 1209 | 577 | 4252 | 0.1357 | -0.3351 |
| MCF7 | PF431396 | 10 | uM | LJP5 | 3 | E07 | 72 | hr | 1209 | 680 | 4376 | 0.1554 | -0.2669 |
| MCF7 | Celastrol | 0.04 | uM | LJP6 | 1 | G12 | 72 | hr | 1209 | 4367 | 3823 | 1.1423 | 1.1669 |
| MCF7 | Celastrol | 0.04 | uM | LJP6 | 2 | G12 | 72 | hr | 1209 | 4019 | 4093 | 0.9817 | 0.9791 |
| MCF7 | Celastrol | 0.04 | uM | LJP6 | 3 | G12 | 72 | hr | 1209 | 4161 | 4121 | 1.0097 | 1.0109 |
| MCF7 | Celastrol | 0.12 | uM | LJP6 | 1 | G11 | 72 | hr | 1209 | 4181 | 3823 | 1.0936 | 1.1108 |
| MCF7 | Celastrol | 0.12 | uM | LJP6 | 2 | G11 | 72 | hr | 1209 | 3894 | 4093 | 0.9512 | 0.9439 |
| MCF7 | Celastrol | 0.12 | uM | LJP6 | 3 | G11 | 72 | hr | 1209 | 3724 | 4121 | 0.9036 | 0.8886 |
| MCF7 | Celastrol | 0.37 | uM | LJP6 | 1 | G10 | 72 | hr | 1209 | 2699 | 3823 | 0.7060 | 0.6217 |
| MCF7 | Celastrol | 0.37 | uM | LJP6 | 2 | G10 | 72 | hr | 1209 | 2698 | 4093 | 0.6590 | 0.5779 |
| MCF7 | Celastrol | 0.37 | uM | LJP6 | 3 | G10 | 72 | hr | 1209 | 2690 | 4121 | 0.6527 | 0.5714 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 1 | G09 | 72 | hr | 1209 | 1399 | 3823 | 0.3659 | 0.0916 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 2 | G09 | 72 | hr | 1209 | 1325 | 4093 | 0.3237 | 0.0532 |