LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Momelotinib | 0.04 | uM | LJP5 | 3 | P12 | 72 | hr | 1209 | 3776 | 4376 | 0.8629 | 0.8471 |
| MCF7 | Momelotinib | 0.12 | uM | LJP5 | 1 | P11 | 72 | hr | 1209 | 3877 | 3980 | 0.9741 | 0.9697 |
| MCF7 | Momelotinib | 0.12 | uM | LJP5 | 2 | P11 | 72 | hr | 1209 | 3912 | 4252 | 0.9199 | 0.9100 |
| MCF7 | Momelotinib | 0.12 | uM | LJP5 | 3 | P11 | 72 | hr | 1209 | 4081 | 4376 | 0.9326 | 0.9261 |
| MCF7 | Momelotinib | 0.37 | uM | LJP5 | 1 | P10 | 72 | hr | 1209 | 3585 | 3980 | 0.9007 | 0.8820 |
| MCF7 | Momelotinib | 0.37 | uM | LJP5 | 2 | P10 | 72 | hr | 1209 | 3629 | 4252 | 0.8533 | 0.8325 |
| MCF7 | Momelotinib | 0.37 | uM | LJP5 | 3 | P10 | 72 | hr | 1209 | 3646 | 4376 | 0.8332 | 0.8126 |
| MCF7 | Momelotinib | 1.11 | uM | LJP5 | 1 | P09 | 72 | hr | 1209 | 2498 | 3980 | 0.6276 | 0.5251 |
| MCF7 | Momelotinib | 1.11 | uM | LJP5 | 2 | P09 | 72 | hr | 1209 | 2946 | 4252 | 0.6927 | 0.6336 |
| MCF7 | Momelotinib | 1.11 | uM | LJP5 | 3 | P09 | 72 | hr | 1209 | 2813 | 4376 | 0.6428 | 0.5761 |
| MCF7 | Momelotinib | 3.33 | uM | LJP5 | 1 | P08 | 72 | hr | 1209 | 1640 | 3980 | 0.4121 | 0.1938 |
| MCF7 | Momelotinib | 3.33 | uM | LJP5 | 2 | P08 | 72 | hr | 1209 | 1747 | 4252 | 0.4108 | 0.2247 |
| MCF7 | Momelotinib | 3.33 | uM | LJP5 | 3 | P08 | 72 | hr | 1209 | 1725 | 4376 | 0.3942 | 0.2109 |
| MCF7 | Momelotinib | 10 | uM | LJP5 | 1 | P07 | 72 | hr | 1209 | 1112 | 3980 | 0.2794 | -0.0478 |
| MCF7 | Momelotinib | 10 | uM | LJP5 | 2 | P07 | 72 | hr | 1209 | 1291 | 4252 | 0.3036 | 0.0366 |
| MCF7 | Momelotinib | 10 | uM | LJP5 | 3 | P07 | 72 | hr | 1209 | 1388 | 4376 | 0.3172 | 0.0770 |
| MCF7 | Fedratinib | 0.04 | uM | LJP5 | 1 | L06 | 72 | hr | 1209 | 3875 | 3980 | 0.9736 | 0.9691 |
| MCF7 | Fedratinib | 0.04 | uM | LJP5 | 2 | L06 | 72 | hr | 1209 | 4438 | 4252 | 1.0436 | 1.0476 |
| MCF7 | Fedratinib | 0.04 | uM | LJP5 | 3 | L06 | 72 | hr | 1209 | 3795 | 4376 | 0.8672 | 0.8521 |
| MCF7 | Fedratinib | 0.12 | uM | LJP5 | 1 | L05 | 72 | hr | 1209 | 3228 | 3980 | 0.8110 | 0.7705 |
| MCF7 | Fedratinib | 0.12 | uM | LJP5 | 2 | L05 | 72 | hr | 1209 | 3893 | 4252 | 0.9154 | 0.9049 |
| MCF7 | Fedratinib | 0.12 | uM | LJP5 | 3 | L05 | 72 | hr | 1209 | 4126 | 4376 | 0.9428 | 0.9375 |
| MCF7 | Fedratinib | 0.37 | uM | LJP5 | 1 | L04 | 72 | hr | 1209 | 3016 | 3980 | 0.7578 | 0.7019 |
| MCF7 | Fedratinib | 0.37 | uM | LJP5 | 2 | L04 | 72 | hr | 1209 | 3393 | 4252 | 0.7978 | 0.7659 |
| MCF7 | Fedratinib | 0.37 | uM | LJP5 | 3 | L04 | 72 | hr | 1209 | 3186 | 4376 | 0.7280 | 0.6855 |