LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 GSK1904529A
0.12
uM
LJP6
 2
H23
 72
hr
 1235 3913 4277 0.9148 0.9030
MDA-MB-231 GSK1904529A
0.12
uM
LJP6
 3
H23
 72
hr
 1235 3982 4583 0.8688 0.8566
MDA-MB-231 GSK1904529A
0.37
uM
LJP6
 1
H22
 72
hr
 1235 4084 4355 0.9376 0.9303
MDA-MB-231 GSK1904529A
0.37
uM
LJP6
 2
H22
 72
hr
 1235 4089 4277 0.9560 0.9503
MDA-MB-231 GSK1904529A
0.37
uM
LJP6
 3
H22
 72
hr
 1235 4088 4583 0.8919 0.8826
MDA-MB-231 GSK1904529A
1.11
uM
LJP6
 1
H21
 72
hr
 1235 3958 4355 0.9087 0.8973
MDA-MB-231 GSK1904529A
1.11
uM
LJP6
 2
H21
 72
hr
 1235 3856 4277 0.9015 0.8875
MDA-MB-231 GSK1904529A
1.11
uM
LJP6
 3
H21
 72
hr
 1235 4084 4583 0.8911 0.8816
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 1
H20
 72
hr
 1235 4527 4355 1.0393 1.0428
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 2
H20
 72
hr
 1235 4296 4277 1.0044 1.0049
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 3
H20
 72
hr
 1235 4289 4583 0.9358 0.9310
MDA-MB-231 GSK1904529A
10
uM
LJP6
 1
H19
 72
hr
 1235 4212 4355 0.9670 0.9634
MDA-MB-231 GSK1904529A
10
uM
LJP6
 2
H19
 72
hr
 1235 4261 4277 0.9962 0.9957
MDA-MB-231 GSK1904529A
10
uM
LJP6
 3
H19
 72
hr
 1235 4188 4583 0.9137 0.9068
MDA-MB-231 Linsitinib
0.04
uM
LJP5
 1
O24
 72
hr
 1235 3867 4474 0.8642 0.8488
MDA-MB-231 Linsitinib
0.04
uM
LJP5
 2
O24
 72
hr
 1235 3487 4578 0.7616 0.7315
MDA-MB-231 Linsitinib
0.04
uM
LJP5
 3
O24
 72
hr
 1235 3969 4929 0.8052 0.7942
MDA-MB-231 Linsitinib
0.12
uM
LJP5
 1
O23
 72
hr
 1235 3792 4474 0.8474 0.8294
MDA-MB-231 Linsitinib
0.12
uM
LJP5
 2
O23
 72
hr
 1235 3709 4578 0.8101 0.7890
MDA-MB-231 Linsitinib
0.12
uM
LJP5
 3
O23
 72
hr
 1235 4146 4929 0.8411 0.8339
MDA-MB-231 Linsitinib
0.37
uM
LJP5
 1
O22
 72
hr
 1235 3520 4474 0.7866 0.7574
MDA-MB-231 Linsitinib
0.37
uM
LJP5
 2
O22
 72
hr
 1235 3781 4578 0.8258 0.8073
MDA-MB-231 Linsitinib
0.37
uM
LJP5
 3
O22
 72
hr
 1235 4060 4929 0.8237 0.8147
MDA-MB-231 Linsitinib
1.11
uM
LJP5
 1
O21
 72
hr
 1235 3576 4474 0.7992 0.7725
MDA-MB-231 Linsitinib
1.11
uM
LJP5
 2
O21
 72
hr
 1235 3609 4578 0.7882 0.7633