LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Luminespib
0.04
uM
LJP5
 3
H18
 72
hr
 1235 867 4929 0.1759 -0.1628
MDA-MB-231 Luminespib
0.12
uM
LJP5
 1
H17
 72
hr
 1235 848 4474 0.1895 -0.1837
MDA-MB-231 Luminespib
0.12
uM
LJP5
 2
H17
 72
hr
 1235 775 4578 0.1693 -0.2189
MDA-MB-231 Luminespib
0.12
uM
LJP5
 3
H17
 72
hr
 1235 904 4929 0.1834 -0.1451
MDA-MB-231 Luminespib
0.37
uM
LJP5
 1
H16
 72
hr
 1235 798 4474 0.1783 -0.2100
MDA-MB-231 Luminespib
0.37
uM
LJP5
 2
H16
 72
hr
 1235 789 4578 0.1723 -0.2115
MDA-MB-231 Luminespib
0.37
uM
LJP5
 3
H16
 72
hr
 1235 913 4929 0.1852 -0.1408
MDA-MB-231 Luminespib
1.11
uM
LJP5
 1
H15
 72
hr
 1235 802 4474 0.1792 -0.2079
MDA-MB-231 Luminespib
1.11
uM
LJP5
 2
H15
 72
hr
 1235 803 4578 0.1754 -0.2041
MDA-MB-231 Luminespib
1.11
uM
LJP5
 3
H15
 72
hr
 1235 815 4929 0.1653 -0.1883
MDA-MB-231 Luminespib
3.33
uM
LJP5
 1
H14
 72
hr
 1235 743 4474 0.1660 -0.2398
MDA-MB-231 Luminespib
3.33
uM
LJP5
 2
H14
 72
hr
 1235 853 4578 0.1863 -0.1782
MDA-MB-231 Luminespib
3.33
uM
LJP5
 3
H14
 72
hr
 1235 792 4929 0.1607 -0.1999
MDA-MB-231 Luminespib
10
uM
LJP5
 1
H13
 72
hr
 1235 612 4474 0.1368 -0.3152
MDA-MB-231 Luminespib
10
uM
LJP5
 2
H13
 72
hr
 1235 715 4578 0.1562 -0.2515
MDA-MB-231 Luminespib
10
uM
LJP5
 3
H13
 72
hr
 1235 763 4929 0.1548 -0.2147
MDA-MB-231 AZD8330
0.04
uM
LJP5
 1
G24
 72
hr
 1235 1414 4474 0.3160 0.0752
MDA-MB-231 AZD8330
0.04
uM
LJP5
 2
G24
 72
hr
 1235 1427 4578 0.3117 0.0790
MDA-MB-231 AZD8330
0.04
uM
LJP5
 3
G24
 72
hr
 1235 1382 4929 0.2804 0.0576
MDA-MB-231 AZD8330
0.12
uM
LJP5
 1
G23
 72
hr
 1235 1162 4474 0.2597 -0.0327
MDA-MB-231 AZD8330
0.12
uM
LJP5
 2
G23
 72
hr
 1235 1392 4578 0.3040 0.0650
MDA-MB-231 AZD8330
0.12
uM
LJP5
 3
G23
 72
hr
 1235 1376 4929 0.2792 0.0553
MDA-MB-231 AZD8330
0.37
uM
LJP5
 1
G22
 72
hr
 1235 1325 4474 0.2961 0.0382
MDA-MB-231 AZD8330
0.37
uM
LJP5
 2
G22
 72
hr
 1235 1393 4578 0.3042 0.0654
MDA-MB-231 AZD8330
0.37
uM
LJP5
 3
G22
 72
hr
 1235 1494 4929 0.3031 0.0997