LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 WZ3105
10
uM
LJP5
 1
D19
 72
hr
 1235 638 4474 0.1426 -0.2997
MDA-MB-231 WZ3105
10
uM
LJP5
 2
D19
 72
hr
 1235 656 4578 0.1433 -0.2849
MDA-MB-231 WZ3105
10
uM
LJP5
 3
D19
 72
hr
 1235 813 4929 0.1649 -0.1893
MDA-MB-231 XMD11-50
0.04
uM
LJP6
 1
P12
 72
hr
 1235 3687 4355 0.8464 0.8247
MDA-MB-231 XMD11-50
0.04
uM
LJP6
 2
P12
 72
hr
 1235 3882 4277 0.9076 0.8946
MDA-MB-231 XMD11-50
0.04
uM
LJP6
 3
P12
 72
hr
 1235 4018 4583 0.8767 0.8655
MDA-MB-231 XMD11-50
0.12
uM
LJP6
 1
P11
 72
hr
 1235 3317 4355 0.7615 0.7215
MDA-MB-231 XMD11-50
0.12
uM
LJP6
 2
P11
 72
hr
 1235 3158 4277 0.7383 0.6884
MDA-MB-231 XMD11-50
0.12
uM
LJP6
 3
P11
 72
hr
 1235 3740 4583 0.8160 0.7961
MDA-MB-231 XMD11-50
0.37
uM
LJP6
 1
P10
 72
hr
 1235 2766 4355 0.6350 0.5578
MDA-MB-231 XMD11-50
0.37
uM
LJP6
 2
P10
 72
hr
 1235 2595 4277 0.6067 0.5131
MDA-MB-231 XMD11-50
0.37
uM
LJP6
 3
P10
 72
hr
 1235 2641 4583 0.5762 0.4942
MDA-MB-231 XMD11-50
1.11
uM
LJP6
 1
P09
 72
hr
 1235 2063 4355 0.4736 0.3257
MDA-MB-231 XMD11-50
1.11
uM
LJP6
 2
P09
 72
hr
 1235 1973 4277 0.4613 0.2984
MDA-MB-231 XMD11-50
1.11
uM
LJP6
 3
P09
 72
hr
 1235 2367 4583 0.5164 0.4101
MDA-MB-231 XMD11-50
3.33
uM
LJP6
 1
P08
 72
hr
 1235 1674 4355 0.3843 0.1817
MDA-MB-231 XMD11-50
3.33
uM
LJP6
 2
P08
 72
hr
 1235 1548 4277 0.3619 0.1339
MDA-MB-231 XMD11-50
3.33
uM
LJP6
 3
P08
 72
hr
 1235 1628 4583 0.3552 0.1569
MDA-MB-231 XMD11-50
10
uM
LJP6
 1
P07
 72
hr
 1235 1099 4355 0.2523 -0.0626
MDA-MB-231 XMD11-50
10
uM
LJP6
 2
P07
 72
hr
 1235 1186 4277 0.2773 -0.0228
MDA-MB-231 XMD11-50
10
uM
LJP6
 3
P07
 72
hr
 1235 1219 4583 0.2660 -0.0073
MDA-MB-231 XMD11-85h
0.04
uM
LJP6
 1
P24
 72
hr
 1235 3343 4355 0.7675 0.7290
MDA-MB-231 XMD11-85h
0.04
uM
LJP6
 2
P24
 72
hr
 1235 3689 4277 0.8625 0.8414
MDA-MB-231 XMD11-85h
0.04
uM
LJP6
 3
P24
 72
hr
 1235 4089 4583 0.8921 0.8829
MDA-MB-231 XMD11-85h
0.12
uM
LJP6
 1
P23
 72
hr
 1235 3918 4355 0.8995 0.8867