LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 NU7441
10
uM
LJP5
 3
C07
 72
hr
 1235 1159 4929 0.2351 -0.0317
MDA-MB-231 OSI-027
0.04
uM
LJP6
 1
E12
 72
hr
 1235 4289 4355 0.9846 0.9830
MDA-MB-231 OSI-027
0.04
uM
LJP6
 2
E12
 72
hr
 1235 4624 4277 1.0810 1.0889
MDA-MB-231 OSI-027
0.04
uM
LJP6
 3
E12
 72
hr
 1235 4643 4583 1.0130 1.0137
MDA-MB-231 OSI-027
0.12
uM
LJP6
 1
E11
 72
hr
 1235 3453 4355 0.7927 0.7600
MDA-MB-231 OSI-027
0.12
uM
LJP6
 2
E11
 72
hr
 1235 4312 4277 1.0081 1.0090
MDA-MB-231 OSI-027
0.12
uM
LJP6
 3
E11
 72
hr
 1235 4469 4583 0.9751 0.9735
MDA-MB-231 OSI-027
0.37
uM
LJP6
 1
E10
 72
hr
 1235 3300 4355 0.7576 0.7167
MDA-MB-231 OSI-027
0.37
uM
LJP6
 2
E10
 72
hr
 1235 4080 4277 0.9539 0.9479
MDA-MB-231 OSI-027
0.37
uM
LJP6
 3
E10
 72
hr
 1235 3739 4583 0.8158 0.7958
MDA-MB-231 OSI-027
1.11
uM
LJP6
 1
E09
 72
hr
 1235 3412 4355 0.7833 0.7485
MDA-MB-231 OSI-027
1.11
uM
LJP6
 2
E09
 72
hr
 1235 3640 4277 0.8510 0.8277
MDA-MB-231 OSI-027
1.11
uM
LJP6
 3
E09
 72
hr
 1235 3327 4583 0.7259 0.6883
MDA-MB-231 OSI-027
3.33
uM
LJP6
 1
E08
 72
hr
 1235 2527 4355 0.5801 0.4822
MDA-MB-231 OSI-027
3.33
uM
LJP6
 2
E08
 72
hr
 1235 2862 4277 0.6691 0.5981
MDA-MB-231 OSI-027
3.33
uM
LJP6
 3
E08
 72
hr
 1235 2608 4583 0.5690 0.4843
MDA-MB-231 OSI-027
10
uM
LJP6
 1
E07
 72
hr
 1235 1451 4355 0.3331 0.0923
MDA-MB-231 OSI-027
10
uM
LJP6
 2
E07
 72
hr
 1235 1604 4277 0.3750 0.1567
MDA-MB-231 OSI-027
10
uM
LJP6
 3
E07
 72
hr
 1235 1720 4583 0.3753 0.1910
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 1
L12
 72
hr
 1235 1962 4355 0.4504 0.2895
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 2
L12
 72
hr
 1235 1932 4277 0.4517 0.2833
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 3
L12
 72
hr
 1235 2251 4583 0.4911 0.3731
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 1
L11
 72
hr
 1235 1729 4355 0.3969 0.2029
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 2
L11
 72
hr
 1235 1583 4277 0.3701 0.1482
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 3
L11
 72
hr
 1235 1741 4583 0.3799 0.1987